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Ori Research Group

Publications

2021

  • Identifying Cell-Type-Specific Metabolic Signatures Using Transcriptome and Proteome Analyses.
    Gebert N, Rahman S, Lewis CA, Ori** A, Cheng** CW
    Curr Protoc 2021, 1(9), e245 ** co-corresponding authors
  • Fetal-like reversion in the regenerating intestine is regulated by mesenchymal Asporin
    Iqbal S, Andersson S, Nestaite E, Pentinmikko N, Kumar A, Borshagovski D, Webb A, Saarinen T, Juuti A, Ori A, Varjosalo M, Pietiläinen KH, Jensen KB, Oudhoff M, Katajisto P
    bioRxiv 2021, https://doi.org/10.1101/2021.06.
  • ATR regulates neuronal activity by modulating presynaptic firing.
    Kirtay M, Sell J, Marx C, Haselmann H, Ceanga M, Zhou ZW, Rahmati V, Kirkpatrick J, Buder K, Grigaravicius P, Ori A, Geis** C, Wang** ZQ
    Nat Commun 2021, 12(1), 4067 ** co-corresponding authors
  • The N-terminal BRCT domain determines MCPH1 function in brain development and fertility.
    Liu* X, Schneble-Löhnert* N, Kristofova M, Qing X, Labisch J, Hofmann S, Ehrenberg S, Sannai M, Jörß T, Ori A, Godmann M, Wang ZQ
    Cell Death Dis 2021, 12(2), 143 * equal contribution
  • Aging drives organ-specific alterations of the inflammatory microenvironment guided by immunomodulatory mediators in mice.
    Schädel P, Troisi F, Czapka A, Gebert N, Pace S, Ori A, Werz O
    FASEB J 2021, 35(5), e21558
  • Extensive remodeling of the extracellular matrix during aging contributes to age-dependent impairments of muscle stem cell functionality.
    Schüler SC, Kirkpatrick* JM, Schmidt* M, Santinha D, Koch P, Di Sanzo S, Cirri E, Hemberg M, Ori** A, von Maltzahn** J
    Cell Rep 2021, 35(10), 109223 * equal contribution, ** co-senior authors
  • HAT cofactor TRRAP modulates microtubule dynamics via SP1 signaling to prevent neurodegeneration.
    Tapias* A, Lázaro* D, Yin* BK, Rasa SMM, Krepelova A, Kelmer Sacramento E, Grigaravicius P, Koch P, Kirkpatrick J, Ori A, Neri F, Wang ZQ
    Elife 2021, 10, e61531 * equal contribution

2020

  • Spatially resolved analysis of FFPE tissue proteomes by quantitative mass spectrometry.
    Buczak K, Kirkpatrick JM, Truckenmueller F, Santinha D, Ferreira L, Roessler S, Singer S, Beck** M, Ori** A
    Nat Protoc 2020, 15(9), 2956-79 ** co-corresponding authors
  • Loss of metabolic plasticity underlies metformin toxicity in aged Caenorhabditis elegans.
    Espada* L, Dakhovnik* A, Chaudhari* P, Martirosyan A, Miek L, Poliezhaieva T, Schaub Y, Nair A, Döring N, Rahnis N, Werz O, Koeberle A, Kirkpatrick J, Ori A, Ermolaeva MA
    Nat Metab 2020, 2(11), 1316-31 * equal contribution
  • Region-specific effects of aging on the small intestinal epithelium and the influence of dietary restriction
    Gebert N
    Dissertation 2020, Jena, Germany