Research Group Valenzano

We broadly study the crosstalk between immune system and commensal microbiota across evolutionary and ontogenetic time scales. In particular, we study how species-specific immune adaptations lead to the selection of specific commensal microbes.

We study functionally how immune aging impacts age-dependent microbiome dysfunction and vice versa how microbiota dynamically impact host immune function and health. We adopt and develop a diversity of methodologies and approaches, ranging from numerical simulations, bioinformatics, genome engineering/editing, computational immunology, population genetics, molecular biology, genomics, as well as wet lab work. Once a year, we conduct field work in Zimbabwe, which hosts the natural habitat of our main model system, the naturally short-lived turquoise killifish (Nothobranchius furzeri).


Dario R. Valenzano
Group Leader
+49 3641 65-6280

Nicole Wolf
+49 3641 65-6339


External Lab Webpage



Dario Riccardo Valenzano+49 3641 656280dario.valenzano@leibniz-fli.deGroup Leader
Silvia Cattelan---silvia.cattelan@leibniz-fli.dePostdoc
Dennis de Bakker---Postdoc
Handan Melike Dönertas---melike.doenertas@leibniz-fli.dePostdoc (external)
Martin Bagic---martin.bagic@leibniz-fli.deDoctoral Candidate
Gabriele Morabito---gabriele.morabito@leibniz-fli.deDoctoral Candidate
Lisa Adam+49 3641 656871lisa.adam@leibniz-fli.deTechnical Assistant

* incomplete due to Data protection