Research Group Valenzano

We broadly study the crosstalk between immune system and commensal microbiota across evolutionary and ontogenetic time scales. In particular, we study how species-specific immune adaptations lead to the selection of specific commensal microbes.

We study functionally how immune aging impacts age-dependent microbiome dysfunction and vice versa how microbiota dynamically impact host immune function and health. We adopt and develop a diversity of methodologies and approaches, ranging from numerical simulations, bioinformatics, genome engineering/editing, computational immunology, population genetics, molecular biology, genomics, as well as wet lab work. Once a year, we conduct field work in Zimbabwe, which hosts the natural habitat of our main model system, the naturally short-lived turquoise killifish (Nothobranchius furzeri).


Dario R. Valenzano
Group Leader
+49 3641 65-6280

Nicole Wolf
+49 3641 65-6401


External Lab Webpage



Dario Riccardo Valenzano+49 3641 656280dario.valenzano@~@leibniz-fli.deGroup Leader
Silvia Cattelan+49 3641 656284silvia.cattelan@~@leibniz-fli.dePostdoc
Dennis de Bakker+49 3641 656702dennis.debakker@~@leibniz-fli.dePostdoc
Kathrin Reichwald+49 3641 656281kathrin.reichwald@~@leibniz-fli.dePostdoc
Alina Ryabova+49 3641 656851alina.ryabova@~@leibniz-fli.dePostdoc
Martin Bagic+49 3641 656851martin.bagic@~@leibniz-fli.deDoctoral Candidate
Gabriele Morabito+49 3641 656702gabriele.morabito@~@leibniz-fli.deDoctoral Candidate
Samuel Allan Kean+49 3641 656851samuel.kean@~@leibniz-fli.deScientist
Lisa Adam+49 3641 656871lisa.adam@~@leibniz-fli.deTechnical Assistant
Farzana Shamim-Schulze+49 3641 656702farzana.shamim-schulze@~@leibniz-fli.deTechnical Assistant

* incomplete due to Data protection