Leibniz Institute on Aging - Fritz Lipmann Institute (FLI)
We conduct research on the biology of aging at the molecular, cellular, and systems levels.
Aging Research at FLI
To study the biological foundations of aging — from molecules to entire organisms - we conduct multi-disciplinary research, combining evolutionary approaches, diverse model systems, and cutting-edge omics technologies.
Institute's Research Infrastructure
... combines state-of-the-art core facilities, core services, animal facilities, and specialized units into a powerful network for excellent research.
Research in Dialogue
Whether scientific conferences, lectures, or events for students and teachers, as well as our series Science & Society, or the Long Night of Sciences, and MINT Festival for the general public – we offer insights into our work in aging research.
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News
Evolution shapes the pace of aging: New software brings aging simulations to researchers’ laptops
Why do some species live for only weeks while others survive for centuries? Researchers at the Leibniz Institute on Aging – Fritz Lipmann Institute (FLI) in Jena have developed AEGIS, a freely available software tool that enables scientists to simulate evolution on a standard computer and investigate how lifespan and aging evolve under different ecological pressures and genetic constraints. Described in a new study published in PLoS Computational Biology, the platform represents years of development and marks an important milestone in the evolutionary biology of aging.
Aging in fast motion: Short-lived fish offer new insights into the aging immune system
Aging causes the immune system to become less effective, increasing susceptibility to infections and age-related diseases. Researchers at the Leibniz Institute on Aging (FLI) in Jena have now created a comprehensive molecular and cellular map of immune aging in a vertebrate using the short-lived turquoise killifish (Nothobranchius furzeri). Using a multi-omics approach, they identified key features of immune aging, including chronic inflammation, DNA damage in progenitor cells, and remodeling of the hematopoietic organ. The study shows that important aspects of immune aging are evolutionarily conserved. This makes the killifish particularly well suited for studying the mechanisms of immune aging and for testing potential interventions.
Postdoc Circle Invites - Interview with Dr. Harald Schuhwerk
Dr. Harald Schuhwerk from Regensburg University Hospital gave a lecture on 26 March 2026 at the Leibniz Institute on Aging - Fritz-Lipmann-Institute (FLI) on the topic “Adaptive plasticity in cancer: integration of DDR restructuring, EMT programmes and immune regulation”.
You can find an interview with Dr. Schuhwerk in this article.
Förderung für Leibniz-Forschungsverbünde und Leibniz-WissenschaftsCampi (Leibniz)
Der Senat der Leibniz-Gemeinschaft bewilligt die Förderung von vier neuen Leibniz-WissenschaftsCampi und verlängert einen Leibniz-WissenschaftsCampus sowie zwei Leibniz-Forschungsverbünde. Diese befassen sich unter anderem mit Klimamodellierung, Antibiotikaresistenzen, gesundem Altern und nachhaltigen Materialien.
Research for a better Aging
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Upcoming Events
FLI Colloquium: Prof. Dr. Dirk Haller
Long Night of Sciences 2026
Girl's and Boy's Day | Forsche Schüler Tag 2026
On April 23, 2026, “Girls' & Boys' Day” will take place in Germany, which will be held on the Beutenberg Campus in Jena as “Forsche Schüler Tag” (Research Students Day). This is a day for students to learn more about science. The FLI once again takes part in this series of events and cordially invites interested students from the 8th grade onwards to a hands-on and information day.
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