recent high impact publications
- Altered translation elongation contributes to key hallmarks of aging in the killifish brain.
Di Fraia* D, Marino* A, Lee* JH, Kelmer Sacramento E, Baumgart M, Bagnoli S, Balla T, Schalk F, Kamrad S, Guan R, Caterino C, Giannuzzi C, Tomaz da Silva P, Sahu AK, Gut H, Siano G, Tiessen M, Terzibasi-Tozzini E, Fornasiero EF, Gagneur J, Englert C, Patil KR, Correia-Melo C, Nedialkova DD, Frydman** J, Cellerino** A, Ori** A
Science 2025, 389(6759), eadk3079 * equal contribution, ** co-senior authors - Prediction of resistance to hydroxyurea therapy in patients with polycythemia vera: a machine learning study (PV-AIM) validated in a prospective interventional phase IV trial (HU-F-AIM).
Heidel* FH, De Stefano V, Zaiss M, Kisro J, Gückel E, Großer S, Zuurman MW, Manz K, Bryan K, Afsharinejad A, Griesshammer M, Kiladjian JJ
Leukemia 2025, 39(7), 1692-701 * corresponding author - p53 reveals principles of chromatin remodeling and enhancer activation.
Fischer M, Schwarz* R, Riege* K, Förste S, Schwab K, Wiechens E, van Bömmel A, Hoffmann S
Nucleic Acids Res 2025, 53(11), gkaf465 * equal contribution - Aging and diet alter the protein ubiquitylation landscape in the mouse brain.
Marino* A, Di Fraia* D, Panfilova D, Sahu AK, Minetti A, Omrani O, Cirri E, Ori A
Nat Commun 2025, 16(1), 5266 * equal contribution - The evolving landscape of epigenetic target molecules and therapies in myeloid cancers: focus on acute myeloid leukemia and myeloproliferative neoplasms.
Kühn MWM, Pemmaraju N, Heidel FH
Leukemia 2025, 39(8), 1824-37 - Embryonic macrophages orchestrate niche cell homeostasis for the establishment of the definitive hematopoietic stem cell pool.
Perçin** G, Riege K, Fröbel J, Metz J, Culemann S, Lesche M, Reinhardt S, Höfer T, Hoffmann S, Waskow** C
Nat Commun 2025, 16(1), 4428 ** co-corresponding authors
