2024

• INHBA is enriched in HPV-negative oropharyngeal squamous cell carcinoma and promotes cancer progression.
  Abou Kors T, Hofmann L, Betzler A, Payer K, Bens M, Truong J, von Witzleben A, Thomas J, Kraus JM, Kalaajieh R, Huber D, Ezić J, Benckendorff J, Greve J, Schuler PJ, Ottensmeier CH, Kestler HA, Hoffmann TK, Theodoraki MN, Brunner C, Laban S
  Cancer Res Commun 2024 (epub ahead of print)
  
• Multi-omics analysis of overexpressed tumor-associated proteins: gene expression, immunopeptide presentation, and antibody response in oropharyngeal squamous cell carcinoma, with a focus on cancer-testis antigens.
  Abou Kors T, Meier M, Mühlenbruch L, Betzler AC, Oliveri F, Bens M, Thomas J, Kraus JM, Doescher J, von Witzleben A, Hofmann L, Ezic J, Huber D, Benckendorff J, Barth TFE, Greve J, Schuler PJ, Brunner C, Blackburn JM, Hoffmann TK, Ottensmeier C, Kestler HA, Rammensee HG, Walz JS, Laban S
  Front Immunol 2024, 15, 1408173
  
• Metabolic modeling reveals the aging-associated decline of host-microbiome metabolic interactions in mice
  Best L, Dost T, Esser D, Flor S, Haase M, Kadibalban AS, Marinos G, Walker A, Zimmermann J, Simon R, Schmidt S, Taubenheim J, Künzel S, Häsler R, Groth M, Waschina S, W.Witte O, Schmitt-Kopplin P, F.Baines J, Frahm C, Kaleta C
  bioRxiv 2024, https://doi.org/10.1101/2024.03.
  
• Cilia defects upon loss of WDR4 are linked to proteasomal hyperactivity and ubiquitin shortage.
  Burkhalter MD, Stiff T, Maerz LD, Casar Tena T, Wiese H, Gerhards J, Sailer SA, Vu LAT, Duong Phu M, Donow C, Alupei M, Iben S, Groth M, Wiese S, Church JA, Jeggo PA, Philipp M
  Cell Death Dis 2024, 15(9), 660
  
• Denervation alters the secretome of myofibers and thereby affects muscle stem cell lineage progression and functionality.
  Henze H, Hüttner SS, Koch P, Schüler SC, Groth M, von Eyss B, von Maltzahn J
  NPJ Regen Med 2024, 9(1), 10
  
• Acetylation-induced proteasomal degradation of the activated glucocorticoid receptor limits hormonal signaling.
  Iyer-Bierhoff A, Wieczorek M, Peter SM, Ward D, Bens M, Vettorazzi S, Guehrs KH, Tuckermann JP, Heinzel T
  iScience 2024, 27(2), 108943
  
• Nonlinear DNA methylation trajectories in aging male mice.
  Olecka* M, van Bömmel* A, Best L, Haase M, Foerste S, Riege K, Dost T, Flor S, Witte OW, Franzenburg S, Groth M, von Eyss B, Kaleta C, Frahm C, Hoffmann S
  Nat Commun 2024, 15(1), 3074 * equal contribution
  
• The Greenland shark (Somniosus microcephalus) genome provides insights into extreme longevity
  Sahm A, Cherkasov* A, Liu* H, Voronov D, Siniuk K, Schwarz R, Ohlenschlaeger O, Foerste S, Bens M, Groth M, Goerlich I, Paturej S, Klages S, Braendl B, Olsen J, Bushnell P, Bech Poulsen A, Ferrando S, Garibaldi F, Lorenzo Drago D, Terzibasi Tozzini E, Mueller FJ, Fischer M, Kretzmer H, Domenici** P, Fleng Steffensen** J, Cellerino** A, Hoffmann** S
  bioRxiv 2024, 10.1101/2024.09.09.611499 * equal contribution, ** co-corresponding authors
  
• The Neurobeachin-like 2 protein (NBEAL2) controls the homeostatic level of the ribosomal protein RPS6 in mast cells.
  Wegner P, Drube J, Ziegler L, Strotmann B, Marquardt R, Küchler C, Groth M, Nieswandt B, Andreas N, Drube S
  Immunology 2024 (epub ahead of print)
  
• Repopulated microglia after pharmacological depletion decrease dendritic spine density in adult mouse brain.
  Wickel J, Chung HY, Ceanga M, von Stackelberg N, Hahn N, Candemir Ö, Baade-Büttner C, Mein N, Tomasini P, Woldeyesus DM, Andreas N, Baumgarten P, Koch P, Groth M, Wang ZQ, Geis C
  Glia 2024 (epub ahead of print)