Current Projects

Our lab focuses on HSCs and hematopoiesis in mice and humans and we use state-of-the art techniques to understand the effect of cell physiological processes on stem and progenitor cell function. We further have a focus on developing optimized tools to address our questions in vivo.

Fundamental unresolved questions that we work on include:

• How is hematopoiesis controlled on the molecular level?
• What keeps a stem cell a stem cell? What invites a stem cell to differentiate?
• What is the role of growth factors in lineage choice?
• How does aging impact hematopoisis and how does hematopoiesis impact aging?

More information about the XpandHSC project supported by the Leibniz Association:

• XpandHSC - Functional Blood Stem Cells (SAW 2020)