von Eyss Research Group
Selected Publications
- TRPS1 shapes YAP/TEAD-dependent transcription in breast cancer cells.
Elster* D, Tollot* M, Schlegelmilch K, Ori A, Rosenwald A, Sahai E, von Eyss B
Nat Commun 2018, 9(1), 3115 * equal contribution - Ubiquitin-Dependent Turnover of MYC Antagonizes MYC/PAF1C Complex Accumulation to Drive Transcriptional Elongation.
Jaenicke* LA, von Eyss* B, Carstensen A, Wolf E, Xu W, Greifenberg AK, Geyer M, Eilers M, Popov N
Mol Cell 2016, 61(1), 54-67 * equal contribution - Repression of SRF target genes is critical for Myc-dependent apoptosis of epithelial cells.
Wiese* KE, Haikala* HM, von Eyss* B, Wolf E, Esnault C, Rosenwald A, Treisman R, Klefström J, Eilers M
EMBO J 2015, 34(11), 1554-71 * equal contribution - A MYC-Driven Change in Mitochondrial Dynamics Limits YAP/TAZ Function in Mammary Epithelial Cells and Breast Cancer.
von Eyss B, Jaenicke LA, Kortlever RM, Royla N, Wiese KE, Letschert S, McDuffus LA, Sauer M, Rosenwald A, Evan GI, Kempa S, Eilers M
Cancer Cell 2015, 28(6), 743-57 - The SNF2-like helicase HELLS mediates E2F3-dependent transcription and cellular transformation.
von Eyss B, Maaskola J, Memczak S, Möllmann K, Schuetz A, Loddenkemper C, Tanh MD, Otto A, Muegge K, Heinemann U, Rajewsky N, Ziebold U
EMBO J 2012, 31(4), 972-85 - The human synMuv-like protein LIN-9 is required for transcription of G2/M genes and for entry into mitosis.
Osterloh* L, von Eyss* B, Schmit F, Rein L, Hübner D, Samans B, Hauser S, Gaubatz S
EMBO J 2007, 26(1), 144-57 * equal contribution
Publications at FLI
2023
- A dysfunctional miR-1-TRPS1-MYOG axis drives ERMS by suppressing terminal myogenic differentiation.
Hüttner SS, Henze H, Elster D, Koch P, Anderer U, von Eyss B, von Maltzahn J
Mol Ther 2023 (epub ahead of print) - Inhibition of the YAP-MMB interaction and targeting NEK2 as potential therapeutic strategies for YAP-driven cancers
Jessen M, Gertzmann D, Liss F, Zenk F, Bähner L, Schöffler V, Ade CP, von Eyss B, Gaubatz S
bioRxiv 2023, 10.1101/2023.07.27.550917 - A noncanonical repressor function of JUN restrains YAP activity and suppresses YAP-dependent liver cancer growth
Kurlishchuk* Y, Cindric Vranesic* A, Jessen* M, Kipping A, Kim K, Cramer P, von Eyss B
bioRxiv 2023, 10.1101/2023.08.20.554005 * equal contribution - Cre recombinase expression cooperates with homozygous FLT3 internal tandem duplication knockin mouse model to induce acute myeloid leukemia.
Straube* J, Eifert* T, Vu T, Janardhanan Y, Haldar R, von Eyss B, Cooper L, Bruedigam C, Ling VY, Cooper E, Patch AM, Bullinger L, Schnoeder TM, Bywater M, Heidel* FH, Lane* SW
Leukemia 2023, 37(4), 741 * equal contribution
2022
- Taz protects hematopoietic stem cells from an aging-dependent decrease in PU.1 activity.
Kim* KM, Mura-Meszaros* A, Tollot* M, Krishnan MS, Gründl M, Neubert L, Groth M, Rodriguez-Fraticelli A, Svendsen AF, Campaner S, Andreas N, Kamradt T, Hoffmann S, Camargo FD, Heidel FH, Bystrykh LV, de Haan G, von Eyss B
Nat Commun 2022, 13(1), 5187 * equal contribution - PLCG1 is required for AML1-ETO leukemia stem cell self-renewal.
Schnoeder TM, Schwarzer A, Jayavelu AK, Hsu CJ, Kirkpatrick J, Döhner K, Perner F, Eifert T, Huber N, Arreba-Tutusaus P, Dolnik A, Assi SA, Nafria M, Jiang L, Dai YT, Chen Z, Chen SJ, Kellaway SG, Ptasinska A, Ng ES, Stanley EG, Elefanty AG, Buschbeck M, Bierhoff H, Brodt S, Matziolis G, Fischer KD, Hochhaus A, Chen CW, Heidenreich O, Mann M, Lane SW, Bullinger L, Ori A, Eyss Bv, Bonifer C, Heidel F
Blood 2022, 139(7), 1080-97
2021
- Genome-wide functional CRISPR-Cas9 screening reveals key roles of GOLT1A and GOLT1B in the FLI-06-mediated secretion block
Cramer P
Dissertation 2021, Jena, Germany - High Yap and Mll1 promote a persistent regenerative cell state induced by Notch signaling and loss of p53.
Heuberger J, Grinat J, Kosel F, Liu L, Kunz S, Vidal RO, Keil M, Haybaeck J, Robine S, Louvard D, Regenbrecht C, Sporbert A, Sauer S, von Eyss B, Sigal M, Birchmeier W
Proc Natl Acad Sci U S A 2021, 118(22) - A comprehensive transcriptome signature of murine hematopoietic stem cell aging.
Svendsen AF, Yang D, Kim KM, Lazare SS, Skinder N, Zwart E, Mura-Meszaros A, Ausema A, Eyss Bv, de Haan G, Bystrykh LV
Blood 2021, 138(6), 439-51
