Rudolph Research Group

Publications

2022

  • Meeting Report: Aging Research and Drug Discovery
    Meron E, Thaysen M, Angeli S, Antebi A, Barzilai N, Baur JA, Bekker-Jensen S, Birkisdottir M, Bischof E, Bruening J, Brunet A, Buchwalter A, Cabreiro F, Cai S, Chen BH, Ermolaeva M, Ewald Collin Y, Ferrucci L, Florian MC, Fortney K, Freund A, Georgievskaya A, Gladyshev VN, Glass D, Golato T, Gorbunova V, Hoejimakers J, Houtkooper RH, Jager S, Jaksch F, Janssens G, Borch Jensen M, Kaeberlein M, Karsenty G, de Keizer P, Kennedy B, Kirkland JL, Kjaer M, Kroemer G, Lee KF, Lemaitre JM, Liaskos D, Longo VD, Lu YX, MacArthur MR, Maier AB, Manakanatas C, Mitchell SJ, Moskalev A, Niedernhofer L, Ozerov I, Partridge L, Passegué E, Petr MA, Peyer J, Radenkovic D, Rando TA, Rattan S, Riedel CG, Rudolph L, Ai R, Serrano M, Schumacher B, Sinclair DA, Smith R, Suh Y, Taub P, Trapp A, Trendelenburg AU, Valenzano DR, Verburgh K, Verdin E, Vijg J, Westendorp RGJ, Zonari A, Bakula D, Zhavoronkov A, Scheibye-Knudsen M
    Aging (Albany NY) 2022, 14(2), 530–543
  • Characterization of Novel α-Mangostin and Paeonol Derivatives With Cancer-Selective Cytotoxicity.
    Nunna S, Huang YP, Rasa M, Krepelova A, Annunziata F, Adam L, Käppel S, Hsu MH, Neri F
    Mol Cancer Ther 2022, 21(2), 257-70
  • Inflammaging is driven by upregulation of innate immune receptors and systemic interferon signaling and is ameliorated by dietary restriction.
    Rasa* SMM, Annunziata* F, Krepelova A, Nunna S, Omrani O, Gebert N, Adam L, Käppel S, Höhn S, Donati G, Jurkowski TP, Rudolph KL, Ori A, Neri F
    Cell Rep 2022, 39(13), 111017 * equal contribution
  • Association of Telomere Length With Risk of Disease and Mortality.
    Schneider CV, Schneider KM, Teumer A, Rudolph KL, Hartmann D, Rader DJ, Strnad P
    JAMA INTERN MED 2022, 182(3), 291-300
  • pH-sensitive packaging of cationic particles by an anionic block copolymer shell.
    Solomun JI, Martin L, Mapfumo P, Moek E, Amro E, Becker F, Tuempel S, Hoeppener S, Rudolph KL, Traeger A
    J Nanobiotechnology 2022, 20(1), 336
  • Age-dependent effects of Igf2bp2 on gene regulation, function, and aging of hematopoietic stem cells in mice.
    Suo M, Rommelfanger MK, Chen Y, Amro EM, Han B, Chen Z, Szafranski K, Chakkarappan SR, Boehm BO, MacLean AL, Rudolph KL
    Blood 2022, 139(17), 2653-65
  • PI(18:1/18:1) is a SCD1-derived lipokine that limits stress signaling.
    Thürmer M, Gollowitzer A, Pein H, Neukirch K, Gelmez E, Waltl L, Wielsch N, Winkler R, Löser K, Grander J, Hotze M, Harder S, Döding A, Meßner M, Troisi F, Ardelt M, Schlüter H, Pachmayr J, Gutiérrez-Gutiérrez Ó, Rudolph KL, Thedieck K, Schulze-Späte U, González-Estévez C, Kosan C, Svatoš A, Kwiatkowski M, Koeberle A
    Nat Commun 2022, 13(1), 2982
  • Identification of dynamic driver sets controlling phenotypical landscapes.
    Werle SD, Ikonomi N, Schwab JD, Kraus JM, Weidner FM, Rudolph KL, Pfister AS, Schuler R, Kühl M, Kestler HA
    Comput Struct Biotechnol J 2022, 20, 1603-17

2021

  • Targeting enzyme aging.
    Becker F, Rudolph KL
    Science 2021, 371(6528), 462-3
  • Transient telomere dysfunction induces chromosomal instability and promotes carcinogenesis.
    Begus-Nahrmann Y, Hartmann D, Kraus J, Eshraghi P, Scheffold A, Grieb M, Rasche V, Schirmacher P, Lee HW, Kestler HA, Lechel A, Rudolph KL
    J Clin Invest 2021, 131(1) Corrigendum for J Clin Invest. 2012;122(6):2283–2288