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A fluorescent folding reporter uncovers myosin misfolding as a driver of Hypertrophic Cardiomyopathy
Arnese R, Julian Dexheimer P, Escobar-Doncel B, Krüger L, Adhikari G, Krpan N, Sehr D, Kley J, Deszcz L, Meinhart A, Kirstein J, Clausen T
bioRxiv 2025, https://doi.org/10.1101/2025.02.
Metabolic modelling reveals the aging-associated decline of host-microbiome metabolic interactions in mice.
Best L, Dost T, Esser D, Flor S, Gamarra AM, Haase M, Kadibalban AS, Marinos G, Walker A, Zimmermann J, Simon R, Schmidt S, Taubenheim J, Künzel S, Häsler R, Franzenburg S, Groth M, Waschina S, Rosenstiel P, Sommer F, Witte OW, Schmitt-Kopplin P, Baines JF, Frahm C, Kaleta C
Nat Microbiol 2025, 10(4), 973-91
Integrative multiomic approaches reveal ZMAT3 and p21 as conserved hubs in the p53 tumor suppression network.
Boutelle AM, Mabene AR, Yao D, Xu H, Wang M, Tang YJ, Lopez SS, Sinha S, Demeter J, Cheng R, Benard BA, McCrea EM, Valente LJ, Drainas AP, Fischer M, Majeti R, Petrov DA, Jackson PK, Yang F, Winslow MM, Bassik MC, Attardi LD
Cell Death Differ 2025 (epub ahead of print)
Rapid brain tumor classification from sparse epigenomic data.
Brändl B, Steiger M, Kubelt C, Rohrandt C, Zhu Z, Evers M, Wang G, Schuldt B, Afflerbach AK, Wong D, Lum A, Halldorsson S, Djirackor L, Leske H, Magadeeva S, Smičius R, Quedenau C, Schmidt NO, Schüller U, Vik-Mo EO, Proescholdt M, Riemenschneider MJ, Zadeh G, Ammerpohl O, Yip S, Synowitz M, van Bömmel** A, Kretzmer** H, Müller** FJ
Nat Med 2025, 31(3), 840-8 ** co-corresponding authors
The microcephaly-associated protein YIPF5 differentially regulates ER-export
Bruno F, Anitei M, Di Fraia D, Durso W, Dau T, Cirri E, Sannai M, Valkova C, Maldutyte J, A.Miller E, Rubio I, Garloff V, Kersten N, Farias G, Ori A, Mestres I, Calegari F, Kaether C
bioRxiv 2025, https://doi.org/10.1101/2025.06.
Age-dependent decline in sperm quality and function in a naturally short-lived vertebrate.
Cattelan** S, Valenzano** DR
BMC Ecol Evol 2025, 25(1), 2 ** co-corresponding authors
Nerve Growth Factor Receptor (NGFR/p75NTR) of the Small-Spotted Catshark (Scyliorhinus canicula): Evolutionary Conservation and Brain Function.
Chiavacci E, Camera R, Costa M, Fronte B, Tozzini ET, Cellerino A
J Comp Neurol 2025, 533(4), e70049
Wilms' tumor 1 impairs apoptotic clearance of fibroblasts in distal fibrotic lung lesions.
Ediga HH, Vemulapalli CP, Sontake V, Patel PK, Miyazaki H, Popov D, Jensen MB, Jegga AG, Huang SK, Englert C, Schedl A, Gupta N, McCormack FX, Madala SK
J Clin Invest 2025 (epub ahead of print)
AnchoRNA: Full virus genome alignments through conserved anchor regions
Eulenfeld** T, Triebel S, Marz** M
bioRxiv 2025, https://doi.org/10.1101/2025.01. ** co-corresponding authors
p53 reveals principles of chromatin remodeling and enhancer activation.
Fischer M, Schwarz* R, Riege* K, Förste S, Schwab K, Wiechens E, van Bömmel A, Hoffmann S
Nucleic Acids Res 2025, 53(11) * equal contribution