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A fluorescent folding reporter uncovers myosin misfolding as a driver of Hypertrophic Cardiomyopathy
Arnese R, Julian Dexheimer P, Escobar-Doncel B, Krüger L, Adhikari G, Krpan N, Sehr D, Kley J, Deszcz L, Meinhart A, Kirstein J, Clausen T
bioRxiv 2025, https://doi.org/10.1101/2025.02.
Analysis of microRNA expression reveals convergent evolution of the molecular control of diapause in annual killifishes.
Barth* E, Baumgart* M, Dolfi* L, Cui R, Groth M, Ripa R, Savino A, Valenzano DR, Platzer M, Marz** M, Cellerino** A
Front Genet 2025, 16, 1583989 * equal contribution, ** co-corresponding authors
Metabolic modelling reveals the aging-associated decline of host-microbiome metabolic interactions in mice.
Best L, Dost T, Esser D, Flor S, Gamarra AM, Haase M, Kadibalban AS, Marinos G, Walker A, Zimmermann J, Simon R, Schmidt S, Taubenheim J, Künzel S, Häsler R, Franzenburg S, Groth M, Waschina S, Rosenstiel P, Sommer F, Witte OW, Schmitt-Kopplin P, Baines JF, Frahm C, Kaleta C
Nat Microbiol 2025, 10(4), 973-91
Placental epigenetic clocks derived from crowdsourcing: Implications for the study of accelerated aging in obstetrics.
Bhatti G, Sufriyana H, Romero R, Patel T, Tekola-Ayele F, Alsaggaf I, Gomez-Lopez N, Su ECY, Done B, Hoffmann S, van Bömmel A, Wan C, Albrecht J, Novak C, DREAM Placenta Clock Challenge Consortium, Chaiworapongsa T, Sirota M, Aghaeepour N, Stolovitzky G, Bryant DR, Tarca AL
iScience 2025, 28(8), 113181
Recombinant Human Neuregulin1-β1 Significantly Reduces Schwannoma Growth in Mice.
Bischoff JP, Schulz A, Hagel C, Büttner R, Reuter M, Bessler WK, Clapp DW, Morrison H
Ann Neurol 2025 (epub ahead of print)
Integrative multiomic approaches reveal ZMAT3 and p21 as conserved hubs in the p53 tumor suppression network.
Boutelle AM, Mabene AR, Yao D, Xu H, Wang M, Tang YJ, Lopez SS, Sinha S, Demeter J, Cheng R, Benard BA, McCrea EM, Valente LJ, Drainas AP, Fischer M, Majeti R, Petrov DA, Jackson PK, Yang F, Winslow MM, Bassik MC, Attardi LD
Cell Death Differ 2025 (epub ahead of print)
Rapid brain tumor classification from sparse epigenomic data.
Brändl B, Steiger M, Kubelt C, Rohrandt C, Zhu Z, Evers M, Wang G, Schuldt B, Afflerbach AK, Wong D, Lum A, Halldorsson S, Djirackor L, Leske H, Magadeeva S, Smičius R, Quedenau C, Schmidt NO, Schüller U, Vik-Mo EO, Proescholdt M, Riemenschneider MJ, Zadeh G, Ammerpohl O, Yip S, Synowitz M, van Bömmel** A, Kretzmer** H, Müller** FJ
Nat Med 2025, 31(3), 840-8 ** co-corresponding authors
The microcephaly-associated protein YIPF5 differentially regulates ER-export
Bruno F, Anitei M, Di Fraia D, Durso W, Dau T, Cirri E, Sannai M, Valkova C, Maldutyte J, A.Miller E, Rubio I, Garloff V, Kersten N, Farias G, Ori A, Mestres I, Calegari F, Kaether C
bioRxiv 2025, https://doi.org/10.1101/2025.06.
Translational Remodeling of the Synaptic Proteome During Aging.
Caterino C, Ugolini M, Durso W, Jevdokimenko K, Groth M, Riege K, Görlach M, Fornasiero E, Ori A, Hoffmann S, Cellerino A
Aging Cell 2025 (epub ahead of print)
Age-dependent decline in sperm quality and function in a naturally short-lived vertebrate.
Cattelan** S, Valenzano** DR
BMC Ecol Evol 2025, 25(1), 2 ** co-corresponding authors