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Ori Research Group

Publications

2023

  • Impact of inflammatory preconditioning on murine microglial proteome response induced by focal ischemic brain injury
    Helbing DL, Haas F, Cirri E, Rahnis N, Thuy Dung Dau T, Kelmer Sacramento E, Oraha N, Böhm L, Morrison H, Bauer R
    bioRxiv 2023, 10.1101/2023.04.13.536755
  • Membrane shapers from two distinct superfamilies cooperate in the development of neuronal morphology.
    Izadi M, Wolf D, Seemann E, Ori A, Schwintzer L, Steiniger F, Kessels MM, Qualmann B
    J Cell Biol 2023, 222(8)
  • Remodeling of the protein ubiquitylation landscape in the aging vertebrate brain
    Marino* A, Di Fraia* D, Panfilova D, Kumar Sahu A, Ori A
    bioRxiv 2023, 10.1101/2023.12.02.569713 * equal contribution
  • IFNγ-Stat1 axis drives aging-associated loss of intestinal tissue homeostasis and regeneration.
    Omrani* O, Krepelova* A, Rasa SMM, Sirvinskas D, Lu J, Annunziata F, Garside G, Bajwa S, Reinhardt S, Adam L, Käppel S, Ducano N, Donna D, Ori A, Oliviero S, Rudolph KL, Neri F
    Nat Commun 2023, 14(1), 6109 * equal contribution
  • Metabololipidomic and proteomic profiling reveals aberrant macrophage activation and interrelated immunomodulatory mediator release during aging.
    Schädel P, Czapka A, Gebert N, Jacobsen ID, Ori** A, Werz** O
    Aging Cell 2023, 22(7), e13856 ** co-corresponding authors
  • Short-Term Caloric Restriction and Subsequent Re-Feeding Compromise Liver Health and Associated Lipid Mediator Signaling in Aged Mice.
    Schädel P, Wichmann-Costaganna M, Czapka A, Gebert N, Ori A, Werz O
    Nutrients 2023, 15(16), 3660
  • Mis-spliced transcripts generate de novo proteins in TDP-43-related ALS/FTD.
    Seddighi S, Qi YA, Brown AL, Wilkins OG, Bereda C, Belair C, Zhang Y, Prudencio M, Keuss MJ, Khandeshi A, Pickles S, Hill SE, Hawrot J, Ramos DM, Yuan H, Roberts J, Sacramento EK, Shah SI, Nalls MA, Colon-Mercado J, Reyes JF, Ryan VH, Nelson MP, Cook C, Li Z, Screven L, Kwan JY, Shantaraman A, Ping L, Koike Y, Oskarsson BR, Staff N, Duong DM, Ahmed A, Secrier M, Ule J, Jacobson S, Rohrer J, Malaspina A, Glass JD, Ori A, Seyfried NT, Maragkakis M, Petrucelli L, Fratta P, Ward ME
    bioRxiv 2023
  • Immunoproteasome function maintains oncogenic gene expression in KMT2A-complex driven leukemia.
    Tubío-Santamaría N, Jayavelu AK, Schnoeder TM, Eifert T, Hsu CJ, Perner F, Zhang Q, Wenge DV, Hansen FM, Kirkpatrick JM, Jyotsana N, Lane SW, von Eyss B, Deshpande AJ, Kühn MWM, Schwaller J, Cammann C, Seifert U, Ebstein F, Krüger E, Hochhaus A, Heuser M, Ori A, Mann M, Armstrong SA, Heidel FH
    Mol Cancer 2023, 22(1), 196

2022

  • Investigating the proteasome interaction network using proximity ligation coupled to mass spectrometry
    Bartolome A
    Dissertation 2022, Jena, Germany
  • ProteasomeID: quantitative mapping of proteasome interactomes and substrates for in vitro and in vivo studies
    Bartolome A, Heiby* JC, Dau* T, Di Fraia D, Heinze I, Kirkpatrick JM, Ori A
    bioRxiv 2022, https://doi.org/10.1101/2022.08. * equal contribution