Publications

2022

• ProteasomeID: quantitative mapping of proteasome interactomes and substrates for in vitro and in vivo studies
  Bartolome A, Heiby* JC, Dau* T, Di Fraia D, Heinze I, Kirkpatrick JM, Ori A
  bioRxiv 2022, https://doi.org/10.1101/2022.08. * equal contribution
  
• Conserved exchange of paralog proteins during neuronal differentiation.
  Di Fraia D, Anitei M, Mackmull MT, Parca L, Behrendt L, Andres-Pons A, Gilmour D, Helmer Citterich M, Kaether C, Beck M, Ori A
  Life Sci Alliance 2022, 5(6)
  
• Metabolic determination of cell fate through selective inheritance of mitochondria.
  Döhla J, Kuuluvainen E, Gebert N, Amaral A, Englund JI, Gopalakrishnan S, Konovalova S, Nieminen AI, Salminen ES, Torregrosa Muñumer R, Ahlqvist K, Yang Y, Bui H, Otonkoski T, Käkelä R, Hietakangas V, Tyynismaa H, Ori A, Katajisto P
  Nat Cell Biol 2022, 24(2), 148-54
  
• The natural compound atraric acid suppresses androgen-regulated neo-angiogenesis of castration-resistant prostate cancer through angiopoietin 2.
  Ehsani M, Bartsch S, Rasa SMM, Dittmann J, Pungsrinont T, Neubert L, Huettner SS, Kotolloshi R, Schindler K, Ahmad A, Mosig AS, Adam L, Ori A, Neri F, Berndt A, Grimm MO, Baniahmad A
  Oncogene 2022, 41(23), 3263-77
  
• Glycation Alters the Fatty Acid Binding Capacity of Human Serum Albumin.
  Henning C, Stübner C, Arabi SH, Reichenwallner J, Hinderberger D, Fiedler R, Girndt M, Di Sanzo S, Ori A, Glomb MA
  J Agric Food Chem 2022, 70(9), 3033-46
  
• Protein lifetimes in aged brains reveal a proteostatic adaptation linking physiological aging to neurodegeneration.
  Kluever V, Russo B, Mandad S, Kumar NH, Alevra M, Ori A, Rizzoli SO, Urlaub H, Schneider A, Fornasiero EF
  Sci Adv 2022, 8(20), eabn4437
  
• Multifaceted Microcephaly-Related Gene MCPH1
  Kristofova M, Ori A, Wang ZQ
  Cells 2022, 11(2), 275
  
• Inflammaging is driven by upregulation of innate immune receptors and systemic interferon signaling and is ameliorated by dietary restriction.
  Rasa* SMM, Annunziata* F, Krepelova A, Nunna S, Omrani O, Gebert N, Adam L, Käppel S, Höhn S, Donati G, Jurkowski TP, Rudolph KL, Ori A, Neri F
  Cell Rep 2022, 39(13), 111017 * equal contribution
  
• Human NMDAR autoantibodies disrupt excitatory-inhibitory balance leading to hippocampal network hypersynchrony
  Schmidl L, Hunter D, Kreye J, Prüss H, Groc L, Hallermann S, Dalmau J, Ori A, Heckmann M, Geis C
  bioRxiv 2022, https://doi.org/10.1101/2022.03.
  
• PLCG1 is required for AML1-ETO leukemia stem cell self-renewal.
  Schnoeder TM, Schwarzer A, Jayavelu AK, Hsu CJ, Kirkpatrick J, Döhner K, Perner F, Eifert T, Huber N, Arreba-Tutusaus P, Dolnik A, Assi SA, Nafria M, Jiang L, Dai YT, Chen Z, Chen SJ, Kellaway SG, Ptasinska A, Ng ES, Stanley EG, Elefanty AG, Buschbeck M, Bierhoff H, Brodt S, Matziolis G, Fischer KD, Hochhaus A, Chen CW, Heidenreich O, Mann M, Lane SW, Bullinger L, Ori A, Eyss Bv, Bonifer C, Heidel F
  Blood 2022, 139(7), 1080-97