Publications

2021

• Novel biochemical, structural and systems insights into inflammatory signaling revealed by contextual interaction proteomics
  Ciuffa R, Uliana F, Mehnert M, Marulli C, Satanowski A, Rodilla Ramírez PN, Meier P, Ori A, Gstaiger M, Aebersold R
  bioRxiv 2021, 10.1101/2021.09.18.460902
  
• Tnfaip2/exoc3-driven lipid metabolism is essential for stem cell differentiation and organ homeostasis.
  Deb S, Felix DA, Koch P, Deb MK, Szafranski K, Buder K, Sannai M, Groth M, Kirkpatrick J, Pietsch S, Gollowitzer A, Groß A, Riemenschneider P, Koeberle A, González-Estévez** C, Rudolph** KL
  EMBO Rep 2021, 22(1), e49328 ** co-corresponding authors
  
• Conserved exchange of paralog proteins during neuronal differentiation
  Di Fraia D, Anitei M, Mackmull MT, Parca L, Behrendt L, Andres-Pons A, Gilmour D, Helmer Citterich M, Kaether C, Beck M, Ori A
  bioRxiv 2021, doi.org/10.1101/2021.07.22.45334
  
• GMPPA defects cause a neuromuscular disorder with α-dystroglycan hyperglycosylation.
  Franzka P, Henze* H, Jung* MJ, Schüler SC, Mittag S, Biskup K, Liebmann L, Kentache T, Morales J, Martínez B, Katona I, Herrmann T, Huebner AK, Hennings JC, Groth S, Gresing LJ, Horstkorte R, Marquardt T, Weis J, Kaether C, Mutchinick OM, Ori A, Huber O, Blanchard V, von Maltzahn J, Hübner CA
  J Clin Invest 2021, 131(9), e139076 * equal contribution
  
• The Hematopoietic Bone Marrow Niche Ecosystem.
  Fröbel J, Landspersky T, Percin G, Schreck C, Rahmig S, Ori A, Nowak D, Essers M, Waskow C, Oostendorp RAJ
  Front Cell Dev Biol 2021, 9, 705410
  
• Identifying Cell-Type-Specific Metabolic Signatures Using Transcriptome and Proteome Analyses.
  Gebert N, Rahman S, Lewis CA, Ori** A, Cheng** CW
  Curr Protoc 2021, 1(9), e245 ** co-corresponding authors
  
• Fetal-like reversion in the regenerating intestine is regulated by mesenchymal Asporin
  Iqbal S, Andersson S, Nestaite E, Pentinmikko N, Kumar A, Borshagovski D, Webb A, Saarinen T, Juuti A, Ori A, Varjosalo M, Pietiläinen KH, Jensen KB, Oudhoff M, Katajisto P
  bioRxiv 2021, https://doi.org/10.1101/2021.06.
  
• ATR regulates neuronal activity by modulating presynaptic firing.
  Kirtay M, Sell J, Marx C, Haselmann H, Ceanga M, Zhou ZW, Rahmati V, Kirkpatrick J, Buder K, Grigaravicius P, Ori A, Geis** C, Wang** ZQ
  Nat Commun 2021, 12(1), 4067 ** co-corresponding authors
  
• The N-terminal BRCT domain determines MCPH1 function in brain development and fertility.
  Liu* X, Schneble-Löhnert* N, Kristofova M, Qing X, Labisch J, Hofmann S, Ehrenberg S, Sannai M, Jörß T, Ori A, Godmann M, Wang ZQ
  Cell Death Dis 2021, 12(2), 143 * equal contribution
  
• Aging drives organ-specific alterations of the inflammatory microenvironment guided by immunomodulatory mediators in mice.
  Schädel P, Troisi F, Czapka A, Gebert N, Pace S, Ori A, Werz O
  FASEB J 2021, 35(5), e21558