Publications

2023

• Metabololipidomic and proteomic profiling reveals aberrant macrophage activation and interrelated immunomodulatory mediator release during aging.
  Schädel P, Czapka A, Gebert N, Jacobsen ID, Ori** A, Werz** O
  Aging Cell 2023, 22(7), e13856 ** co-corresponding authors
  
• Short-Term Caloric Restriction and Subsequent Re-Feeding Compromise Liver Health and Associated Lipid Mediator Signaling in Aged Mice.
  Schädel P, Wichmann-Costaganna M, Czapka A, Gebert N, Ori A, Werz O
  Nutrients 2023, 15(16), 3660
  
• Immunoproteasome function maintains oncogenic gene expression in KMT2A-complex driven leukemia.
  Tubío-Santamaría N, Jayavelu AK, Schnoeder TM, Eifert T, Hsu CJ, Perner F, Zhang Q, Wenge DV, Hansen FM, Kirkpatrick JM, Jyotsana N, Lane SW, von Eyss B, Deshpande AJ, Kühn MWM, Schwaller J, Cammann C, Seifert U, Ebstein F, Krüger E, Hochhaus A, Heuser M, Ori A, Mann M, Armstrong SA, Heidel FH
  Mol Cancer 2023, 22(1), 196
  

2022

• Investigating the proteasome interaction network using proximity ligation coupled to mass spectrometry
  Bartolome A
  Dissertation 2022, Jena, Germany
  
• Novel biochemical, structural, and systems insights into inflammatory signaling revealed by contextual interaction proteomics.
  Ciuffa R, Uliana F, Mannion J, Mehnert M, Tenev T, Marulli C, Satanowski A, Keller LML, Rodilla Ramírez PN, Ori A, Gstaiger M, Meier P, Aebersold R
  Proc Natl Acad Sci U S A 2022, 119(40), e2117175119
  
• Conserved exchange of paralog proteins during neuronal differentiation.
  Di Fraia D, Anitei M, Mackmull MT, Parca L, Behrendt L, Andres-Pons A, Gilmour D, Helmer Citterich M, Kaether C, Beck M, Ori A
  Life Sci Alliance 2022, 5(6), e202201397
  
• Metabolic determination of cell fate through selective inheritance of mitochondria.
  Döhla J, Kuuluvainen E, Gebert N, Amaral A, Englund JI, Gopalakrishnan S, Konovalova S, Nieminen AI, Salminen ES, Torregrosa Muñumer R, Ahlqvist K, Yang Y, Bui H, Otonkoski T, Käkelä R, Hietakangas V, Tyynismaa H, Ori A, Katajisto P
  Nat Cell Biol 2022, 24(2), 148-54
  
• The natural compound atraric acid suppresses androgen-regulated neo-angiogenesis of castration-resistant prostate cancer through angiopoietin 2.
  Ehsani M, Bartsch S, Rasa SMM, Dittmann J, Pungsrinont T, Neubert L, Huettner SS, Kotolloshi R, Schindler K, Ahmad A, Mosig AS, Adam L, Ori A, Neri F, Berndt A, Grimm MO, Baniahmad A
  Oncogene 2022, 41(23), 3263-77
  
• Organelle dysfunction and its contribution to metabolic impairments in aging and age-related diseases
  Heiby JC, Ori A
  Current Opinion in Systems Biology 2022, 30, 10041
  
• Glycation Alters the Fatty Acid Binding Capacity of Human Serum Albumin.
  Henning C, Stübner C, Arabi SH, Reichenwallner J, Hinderberger D, Fiedler R, Girndt M, Di Sanzo S, Ori A, Glomb MA
  J Agric Food Chem 2022, 70(9), 3033-46