Former Research Group - Große



  • Segregation of replicative DNA polymerases during S phase: DNA polymerase ε, but not DNA polymerases α/δ, are associated with lamins throughout S phase in human cells.
    Vaara M, Itkonen H, Hillukkala T, Liu Z, Nasheuer HP, Schaarschmidt D, Pospiech H, Syväoja JE
    J Biol Chem 2012, 287(40), 33327-38


  • Human DHX9 helicase preferentially unwinds RNA-containing displacement loops (R-loops) and G-quadruplexes.
    Chakraborty P, Grosse F
    DNA Repair 2011, 10(6), 654-65
  • Molecular and biochemical properties of the S-layer protein from the wine bacterium Lactobacillus hilgardii B706.
    Dohm N, Petri A, Schlander M, Schlott B, König H, Claus H
    Arch Microbiol 2011, 193(4), 251-61
  • Determination of hemin-binding characteristics of proteins by a combinatorial peptide library approach.
    Kühl T, Sahoo N, Nikolajski M, Schlott B, Heinemann SH, Imhof D
    Chembiochem 2011, 12(18), 2846-55
  • In vitro gap-directed translesion DNA synthesis of an abasic site involving human DNA polymerases epsilon, lambda, and beta.
    Villani G, Hubscher U, Gironis N, Parkkinen S, Pospiech H, Shevelev I, di Cicco G, Markkanen E, Syväoja JE, Tanguy Le Gac N
    J Biol Chem 2011, 286(37), 32094-104


  • Biochemische und funktionelle Charakterisierung der Interaktion des Tumorsuppressorproteins p53 und der Peptidyl-prolyl cis/trans Isomerase Cyslophilin 18
    Baum N
    Dissertation 2010, Jena, Germany
  • Substrate Preferences of the Human DHX9 Helicase
    Chakraborty P
    Dissertation 2010, Jena, Germany
  • WRN helicase unwinds Okazaki fragment-like hybrids in a reaction stimulated by the human DHX9 helicase.
    Chakraborty P, Grosse F
    Nucleic Acids Res 2010, 38(14), 4722-30
  • Containment of extended length polymorphisms in silk proteins.
    Chinali A, Vater W, Rudakoff B, Sponner A, Unger E, Grosse F, Guehrs KH, Weisshart K
    J Mol Evol 2010, 70(4), 325-38
  • Structure and biochemical analysis of the heparin-induced E1 dimer of the amyloid precursor protein.
    Dahms SO, Hoefgen S, Roeser D, Schlott B, Gührs KH, Than ME
    Proc Natl Acad Sci U S A 2010, 107(12), 5381-6