Former Research Group - Große



  • Cell cycle dependent architecture of CENP-A containing centromeric chromatin and its regulation
    Kamweru PK
    Dissertation 2015, Jena, Germany
  • High levels of RAD51 perturb DNA replication elongation and cause unscheduled origin firing due to impaired CHK1 activation.
    Parplys AC, Seelbach JI, Becker S, Behr M, Jend C, Mansour WY, Joosse S, Stuerzbecher HW, Pospiech H, Petersen C, Dikomey E, Borgmann K
    Cell Cycle 2015, 14(19), 3190-202
  • High levels of TopBP1 induce ATR-dependent shut-down of rRNA transcription and nucleolar segregation.
    Sokka M, Rilla K, Miinalainen I, Pospiech H, Syväoja JE
    Nucleic Acids Res 2015, 43(10), 4975-89
  • Structure and regulatory role of the C-terminal winged helix domain of the archaeal minichromosome maintenance complex.
    Wiedemann C, Szambowska A, Häfner S, Ohlenschläger O, Gührs KH, Görlach M
    Nucleic Acids Res 2015, 43(5), 2958-67


  • Kinesin-dependent motility generation as target mechanism of cadmium intoxication.
    Böhm KJ
    Toxicol Lett 2014, 224(3), 356-61
  • The intrinsically disordered amino-terminal region of human RecQL4: multiple DNA-binding domains confer annealing, strand exchange and G4 DNA binding.
    Keller H, Kiosze K, Sachsenweger J, Haumann S, Ohlenschläger O, Nuutinen T, Syväoja J, Görlach M, Grosse F, Pospiech H
    Nucleic Acids Res 2014, 42(20), 12614-27
  • Using cells as biochemical test tubes: Comment on "Biomolecular dynamics and binding studies in the living cell" by Stephan Diekmann and Christian Hoischen.
    Koalick D, Grosse F
    Phys Life Rev 2014, 11(1), 33-5
  • Suppression of the DHX9 helicase induces premature senescence in human diploid fibroblasts in a p53-dependent manner.
    Lee T, Di Paola D, Malina A, Mills JR, Kreps A, Grosse F, Tang H, Zannis-Hadjopoulos M, Larsson O, Pelletier J
    J Biol Chem 2014, 289(33), 22798-814
  • Caspase-3 and Caspase-6 cleave STAT1 in leukemic cells.
    Licht* V, Noack* K, Schlott B, Förster M, Schlenker Y, Licht A, Krämer OH, Heinzel T
    Oncotarget 2014, 5(8), 2305-17 * equal contribution
  • The Ca2+ sensor protein swiprosin-1/EFhd2 is present in neurites and involved in kinesin-mediated transport in neurons.
    Purohit P, Perez-Branguli F, Prots I, Borger E, Gunn-Moore F, Welzel O, Loy K, Wenzel EM, Grömer TW, Brachs S, Holzer M, Buslei R, Fritsch K, Regensburger M, Böhm KJ, Winner B, Mielenz D
    PLoS One 2014, 9(8), e103976