Wang Research Group



  • ASPM promotes ATR-CHK1 activation and stabilizes stalled replication forks in response to replication stress.
    Wu* X, Xu* S, Wang P, Wang ZQ, Chen H, Xu X, Peng B
    Proc Natl Acad Sci U S A 2022, 119(40), e2203783119 * equal contribution
  • PARP1: Liaison of Chromatin Remodeling and Transcription.
    Zong W, Gong Y, Sun W, Li T, Wang ZQ
    Cancers (Basel) 2022, 14(17)


  • Nbs1-mediated DNA damage repair pathway regulates haematopoietic stem cell development and embryonic haematopoiesis.
    Chen Y, Sun J, Ju Z, Wang ZQ, Li T
    Cell Prolif 2021, 54(3), e12972
  • Mapping protein carboxymethylation sites provides insights into their role in proteostasis and cell proliferation.
    Di Sanzo* S, Spengler* K, Leheis A, Kirkpatrick JM, Rändler TL, Baldensperger T, Dau T, Henning C, Parca L, Marx C, Wang ZQ, Glomb MA, Ori** A, Heller** R
    Nat Commun 2021, 12(1), 6743 * equal contribution, ** co-senior authors
  • Establishment of a fluorescent reporter of RNA-polymerase II activity to identify dormant cells
    Freter R, Falletta P, Omrani O, Rasa M, Herbert K, Annunziata F, Minetti A, Krepelova A, Adam L, Käppel S, Rüdiger T, Wang ZQ, Goding** CR, Neri** F
    Nat Commun 2021, 12(1), 3318 ** co-corresponding authors
  • Cell Type-Specific Role of RNA Nuclease SMG6 in Neurogenesis.
    Guerra GM, May D, Kroll T, Koch P, Groth M, Wang** ZQ, Li TL, Grigaravičius** P
    Cells 2021, 10(12), 3365 ** co-corresponding authors
  • The function of ATR in post-mitotic neurons and brain homeostasis
    Kirtay M
    Dissertation 2021, Jena, Germany
  • ATR regulates neuronal activity by modulating presynaptic firing.
    Kirtay M, Sell J, Marx C, Haselmann H, Ceanga M, Zhou ZW, Rahmati V, Kirkpatrick J, Buder K, Grigaravicius P, Ori A, Geis** C, Wang** ZQ
    Nat Commun 2021, 12(1), 4067 ** co-corresponding authors
  • MCPH1, beyond its role deciding the brain size.
    Kristofova M, Wang ZQ
    Aging (Albany NY) 2021, 13(20), 23437-9
  • The Role of the Pathogen Dose and PI3Kγ in Immunometabolic Reprogramming of Microglia for Innate Immune Memory.
    Lajqi T, Marx C, Hudalla H, Haas F, Große S, Wang ZQ, Heller R, Bauer M, Wetzker R, Bauer R
    Int J Mol Sci 2021, 22(5)