Former Research Group - Than (until 2015)
Publications
2012
- Röntgenstrukturanalyse des extrazellulären Cystein-reichen Bereichs des death receptor 6 (DR6) und die Entwicklung einer affinitätsbasierten Reinigung der Proproteinkonvertase Furin
Küster M
Dissertation 2012, Jena, Germany
2011
- Specific amino acids in the BAR domain allow homodimerization and prevent heterodimerization of sorting nexin 33.
Dislich B, Than ME, Lichtenthaler SF
Biochem J 2011, 433(1), 75-83 - Purification of the proprotein convertase furin by affinity chromatography based on PC-specific inhibitors.
Kuester M, Becker GL, Hardes K, Lindberg I, Steinmetzer T, Than ME
Biol Chem 2011, 392(11), 973-81 - The crystal structure of death receptor 6 (DR6): a potential receptor of the amyloid precursor protein (APP).
Kuester M, Kemmerzehl S, Dahms SO, Roeser D, Than ME
J Mol Biol 2011, 409(2), 189-201 - New furin inhibitors based on weakly basic amidinohydrazones.
Sielaff F, Than ME, Bevec D, Lindberg I, Steinmetzer T
Bioorg Med Chem Lett 2011, 21(2), 836-40
2010
- Potent inhibitors of furin and furin-like proprotein convertases containing decarboxylated P1 arginine mimetics.
Becker GL, Sielaff F, Than ME, Lindberg I, Routhier S, Day R, Lu Y, Garten W, Steinmetzer T
J Med Chem 2010, 53(3), 1067-75 - Structure and biochemical analysis of the heparin-induced E1 dimer of the amyloid precursor protein.
Dahms SO, Hoefgen S, Roeser D, Schlott B, Gührs KH, Than ME
Proc Natl Acad Sci U S A 2010, 107(12), 5381-6 - ALS-associated fused in sarcoma (FUS) mutations disrupt Transportin-mediated nuclear import.
Dormann D, Rodde R, Edbauer D, Bentmann E, Fischer I, Hruscha A, Than ME, Mackenzie IRA, Capell A, Schmid B, Neumann M, Haass C
EMBO J 2010, 29(16), 2841-57
2007
- Crystal structure of the human carboxypeptidase N (kininase I) catalytic domain.
Keil C, Maskos K, Than M, Hoopes JT, Huber R, Tan F, Deddish PA, Erdös EG, Skidgel RA, Bode W
J Mol Biol 2007, 366(2), 504-16 published during change of institution
