Former Research Group - Herrlich (until 2022)



  • Protein-tyrosine phosphatase DEP-1 controls receptor tyrosine kinase FLT3 signaling.
    Arora D, Stopp S, Böhmer SA, Schons J, Godfrey R, Masson K, Razumovskaya E, Rönnstrand L, Tänzer S, Bauer R, Böhmer FD, Müller JP
    J Biol Chem 2011, 286(13), 10918-29
  • Epidermal growth factor (EGF) ligand release by substrate-specific a disintegrin and metalloproteases (ADAMs) involves different protein kinase C (PKC) isoenzymes depending on the stimulus.
    Dang M, Dubbin K, D'Aiello A, Hartmann M, Lodish H, Herrlich A
    J Biol Chem 2011, 286(20), 17704-13
  • Multifactorial analysis of individual radiosensitivity
    Dreffke K
    Dissertation 2011, Jena, Germany
  • Oxidative inactivation of DEP-1/PTPRJ as a novel transforming principle in FLT3 ITD-inducted Acute Myeloid Leukemia (AML)
    Godfrey R
    Dissertation 2011, Jena, Germany
  • Modulation of mutant huntingtin N-terminal cleavage and its effect on aggregation and cell death.
    Juenemann K, Weisse C, Reichmann D, Kaether C, Calkhoven CF, Schilling G
    Neurotox Res 2011, 20(2), 120-33
  • A radiation-induced gene expression signature as a tool to predict acute radiotherapy-induced adverse side effects.
    Mayer C, Popanda O, Greve B, Fritz E, Illig T, Eckardt-Schupp F, Gomolka M, Benner A, Schmezer P
    Cancer Lett 2011, 302(1), 20-8
  • Activation of Ras requires the ERM-dependent link of actin to the plasma membrane.
    Sperka T, Geissler KJ, Merkel U, Scholl I, Rubio I, Herrlich P, Morrison HL
    PLoS One 2011, 6(11), e27511


  • Radiation Induced Cytoplasmic Signaling
    Böhmer FD, Weiss C, Herrlich P
    In: Handbook of Cell Signaling (edited by Ralph A. Bradshaw and Edward A. Dennis) 2010, Volume 3(Chapter 267), 2225-30, Elsevier Inc. Academic
  • The nuclear isoform of the LIM domain protein Trip6 integrates activating and repressing signals at the promoter-bound glucocorticoid receptor.
    Diefenbacher ME, Litfin M, Herrlich P, Kassel O
    Mol Cell Endocrinol 2010, 320(1-2), 58-66


  • Multicentric investigation of ionising radiation-induced cell death as a predictive parameter of individual radiosensitivity.
    Greve* B, Dreffke* K, Rickinger* A, Könemann S, Fritz E, Eckardt-Schupp F, Amler S, Sauerland C, Braselmann H, Sauter W, Illig T, Schmezer P, Gomolka M, Willich N, Bölling T
    Apoptosis 2009, 14(2), 226-35 * equal contribution

Best Paper

The JBC paper on Ectodomain Cleavage was selected as one of the best JBC papers of the year.