Former Research Group - Herrlich (until 2022)

Publications

2017

  • Spindle Misorientation of Cerebral and Cerebellar Progenitors Is a Mechanistic Cause of Megalencephaly.
    Li H, Kroll T, Moll J, Frappart L, Herrlich P, Heuer H, Ploubidou A
    Stem Cell Reports 2017, 9(4), 1071-80

2016

  • Impaired Planar Germ Cell Division in the Testis, Caused by Dissociation of RHAMM from the Spindle, Results in Hypofertility and Seminoma.
    Li H, Frappart* L, Moll* J, Winkler* A, Kroll T, Hamann J, Kufferath I, Groth M, Taudien S, Schütte M, Yaspo ML, Heuer H, Lange BMH, Platzer M, Zatloukal K, Herrlich P, Ploubidou A
    Cancer Res 2016, 76(21), 6382-95 * equal contribution
  • Growth factor and co-receptor release by structural regulation of substrate metalloprotease accessibility.
    Parra* LM, Hartmann* M, Schubach S, Ma J, Herrlich** P, Herrlich** A
    Sci Rep 2016, 6, 37464 * equal contribution, ** co-senior authors

2015

  • Inside-out Regulation of Ectodomain Cleavage of Cluster-of-Differentiation-44 [CD44] and of Neuregulin-1 requires Substrate Dimerization.
    Hartmann M, Parra LM, Ruschel A, Lindner C, Morrison H, Herrlich** A, Herrlich** P
    J Biol Chem 2015, 290(28), 17041-54 ** co-senior authors, 2015 Best of jbc Papers of the Week Winner
  • Tumor suppressor NF2 blocks cellular migration by inhibiting ectodomain cleavage of CD44.
    Hartmann* M, Parra* LM, Ruschel A, Schubert S, Li Y, Morrison H, Herrlich** A, Herrlich** P
    Mol Cancer Res 2015, 13(5), 879-90 * equal contribution, ** co-senior authors
  • RHAMM deficiency disrupts folliculogenesis resulting in female hypofertility.
    Li H, Moll J, Winkler A, Frappart L, Brunet S, Hamann J, Kroll T, Verlhac MH, Heuer H, Herrlich P, Ploubidou A
    Biol Open 2015, 4(4), 562-71
  • Distinct Intracellular Domain Substrate Modifications Selectively Regulate Ectodomain Cleavage of NRG1 or CD44
    Parra* LM, Hartmann* M, Schubach S, Li Y, Herrlich P, Herrlich A
    Mol Cell Biol 2015, 35(19), 3381-95 * equal contribution
  • The co-receptor function of CD44v6 and the effect of conditional deletion of CD44 isoforms on wound healing
    Ruschel A
    Dissertation 2015, Jena, Germany

2014

  • The LIM Domain Protein nTRIP6 Recruits the Mediator Complex to AP-1-Regulated Promoters.
    Diefenbacher* ME, Reich* D, Dahley O, Kemler D, Litfin M, Herrlich P, Kassel O
    PLoS One 2014, 9(5), e97549 * equal contribution
  • CD44 controls gene expression levels via two independent molecular actions
    Lindner C
    Dissertation 2014, Jena, Germany

Best Paper

The JBC paper on Ectodomain Cleavage was selected as one of the best JBC papers of the year.