Dietary restriction (DR) is known to be the most powerful intervention to delay aging across species. However, recent studies from our lab indicate that DR is less effective at improving the…
In a second focus of our work, we are investigating aging-associated changes in metabolism in stem cells and organs. Our work has identified an age-dependent decline in fat metabolism in the liver.…
We aim to mechanistically understand how early life stress (such as metabolic activity as well as growth factor signaling or inflammatory signaling) creates a memory in stem cells and tissues. We…
Another line of research in our lab focuses on the question whether growth and metabolism at an early age influence the aging trajectories of stem cells and metabolic aging in later life. Our work…
Programme
We would like to inform you that the DGfA Meeting 2023 will start at 12.25 pm on June 29th with opening remarks. The meeting will finish at 1.30 pm, on June 30th, followed by the…
On May 8, 2023, for first time, the "Jena Microbiome Meeting 2023" (JMM 2023) took place at the Leibniz Institute on Aging - Fritz Lipmann Institute (FLI). This meeting was initiated and organized by…
Vision
Sustainable Research Data Management (RDM) is maintained and disseminated at the FLI, including documentation as well as Best Practices organizing, sharing, backups, and archiving of…
Am 23. Mai 2023 findet von 15 bis 19 Uhr in der Jenaer Innenstadt der 10. Tag der Vielfalt statt, zu dem wir alle Interessierten - ob groß oder klein - ganz herzlich einladen.
Tag der Vielfalt in der…
New research in the African killifish reveals that towards the end of life, our muscles actually reverse to an “early-life” state, with clues to preventing muscle wasting
As we age, our muscles start…