Rudolph Research Group



  • Glucose substitution prolongs maintenance of energy homeostasis and lifespan of telomere dysfunctional mice.
    Missios P, Zhou Y, Guachalla LM, von Figura G, Wegner A, Chakkarappan SR, Binz T, Gompf A, Hartleben G, Burkhalter MD, Wulff V, Günes C, Sattler RW, Song Z, Illig T, Klaus S, Böhm BO, Wenz T, Hiller K, Rudolph KL
    Nat Commun 2014, 5, 4924
  • Substantial telomere shortening in the substantia nigra of telomerase-deficient mice does not increase susceptibility to MPTP-induced dopamine depletion.
    Oeckl P, Scheffold A, Lechel A, Rudolph KL, Ferger B
    Neuroreport 2014, 25(5), 335-9 published during change of institution
  • Effect of cytotoxic chemotherapy on markers of molecular age in patients with breast cancer.
    Sanoff HK, Deal AM, Krishnamurthy J, Torrice C, Dillon P, Sorrentino J, Ibrahim JG, Jolly TA, Williams G, Carey LA, Drobish A, Gordon BB, Alston S, Hurria A, Kleinhans K, Rudolph KL, Sharpless NE, Muss HB
    J Natl Cancer Inst 2014, 106(4), dju057
  • Aging stem cells: transcriptome meets epigenome meets methylome.
    Tümpel S, Rudolph KL
    Cell Stem Cell 2014, 14(5), 551-2
  • Senescence and apoptosis block hematopoietic activation of quiescent hematopoietic stem cells with short telomeres.
    Wang J, Lu X, Sakk V, Klein CA, Rudolph KL
    Blood 2014, 124(22), 3237-40
  • Exonuclease 1 is essential for maintaining genomic stability and the proliferative capacity of neural but not hematopoietic stem cells.
    Zhang J, Yang R, Zhou D, Rudolph KL, Meng A, Ju Z
    Stem Cell Res 2014, 12(1), 250-9


  • Telomere stability--Wnt it or lose it.
    Bauer K, Tao S, Rudolph KL
    EMBO Rep 2013, 14(4), 297-8
  • Quantitative proteomic profiling of tumor cell response to telomere dysfunction using isotope-coded protein labeling (ICPL) reveals interaction network of candidate senescence markers.
    Biniossek ML, Lechel A, Rudolph KL, Martens UM, Zimmermann S
    J Proteomics 2013, 91, 515-35 published during change of institution
  • Grk5l Controls Heart Development by Limiting mTOR Signaling during Symmetry Breaking.
    Burkhalter MD, Fralish GB, Premont RT, Caron MG, Philipp M
    Cell Rep 2013, 4(4), 625-32
  • Are aging biomarkers clinically relevant in oncogeriatrics?
    Falandry C, Gilson E, Rudolph KL
    Crit Rev Oncol Hematol 2013, 85(3), 257-65 published during change of institution