Tryptophan metabolism plays a pivotal role in linking immune, metabolic, and neurocognitive processes across the lifespan. Alterations in its key branching pathways, such as serotonin, kynurenines, and indoles, have been implicated in a range of chronic diseases, neuroinflammation, and age-related disorders.
This talk explores tryptophan metabolism as a dynamic immunometabolic system, extending beyond disease-specific mechanisms to encompass the broader mind-brain-body axis. Drawing on recent research, including his own, Lim will highlight the value of profiling these pathways across the lifespan using systems biology approaches. This perspective supports precision medicine and holistic treatment strategies aimed at improving health outcomes and predicting treatment responses, including mental health aspects, in aging and chronic disease.
Lim is the Professor of Translational Child and Adolescent Psychiatry at University Hospital Jena. He currently serves as Secretary and Treasurer of the International Society for Tryptophan Research (ISTRY).
| Talk: | Altered tryptophan metabolism in neuroinflammation and aging | |
| Speaker: | Prof. Dr. Edwin Lim University Hospital Jena | |
| Date: | Thursday, May 15th, 2025 at 3 pm | |
| Location: | Seminar room „Nucleus“, FLI 1, Beutenbergstraße 11, Jena | |
| Host: | K. Lenhard Rudolph |
The seminar will take place in person only.
For external guests: Please email Gundula Bergner for details.
