Phosphatidylinositol-specific phospholipase C (PLC) belongs to a group of enzymes that catalyze hydrolysis of phosphatidylinositol 4,5-bisphosphate. Through that process, the second messenger…
A key characteristic of hematopoietic stem cells (HSC) is the ability to self-renew. Several genes and signaling pathways control the fine balance between self-renewal and differentiation in HSC and…