Our lab focuses on HSCs and hematopoiesis in mice and humans and we use state-of-the art techniques to understand the effect of cell physiological processes on stem and progenitor cell function. We…
Englert Research Group
Current Projects
Identification of targets of the Wilms tumor protein Wt1 in tissue development and homeostasis Characterization of Wt1’s function in the central…
Posttranslational modification (PTMs) of transcription factors (TFs) and histones are critical mechanisms for regulating the genomic activity. For some TFs, chemical alterations of lysines are…
The ability to maintain a functional proteome declines during the aging process, which results in dysregulated protein homeostasis and the accumulation of damaged, misfolded, and partially…
The anti-aging protein Klotho is strongly expressed in kidney and choroid plexus (CP). In kidney, Klotho full length functions as a co-receptor for the hormone FGF23. In addition, the external part…
DFG Research Training Groups
The graduate college (GRK) aims at investigating key mechanisms of aging: posttranslational modifications (PTMs) of cellular proteins. It offers an innovative…
Jena Centre for Bioinformatics
The Jena Centre for Bioinformatics (JCB) has its roots in a BMBF funding initiative (project period 2001-2008) comprising university and non-university institutions as…