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671. License for cutting: How intracellular signaling regulates growth factor production

Cancer cells need life-essential molecules to proliferate. These growth factors are activated by ectodomain shedding of precursor proteins on the outside of plasma membrane, mainly carried out by

672. Loss of microRNA leads to fibrosis

Fibrosis describes a pathological stiffening of organs or tissues that is caused by the increased synthesis of extracellular proteins. Fibrosis severely impairs organ function and may occur in

673. FLI researcher receives Chan Zuckerberg Initiative grant for research on neurodegenerative diseases

The Chan Zuckerberg Initiative (CZI) announced $4.5 million in funding to support 30 pairs of researchers to collaborate and apply novel approaches for gaining greater insight into neurodegenerative

674. Cancer cachexia: Extracellular ligand helps to prevent muscle loss

Cancer cachexia is a complex metabolic disease accounting for approximately one third of all cancer-related deaths worldwide. So far, there is no effective therapy for this muscle wasting disease.

675. Postdocs

On the Way to Becoming a Senior: Postdocs at FLI Currently, more than 40 postdocs are working at the FLI. To provide them with a well-structured, interdisciplinary network, FLI founded the

676. History

How It All Started: ZIMET and IMB The origins of FLI go back to the period of the German Democratic Republic (GDR). The “Central Institute for Microbiology and Experimental Therapy – ZIMET” on the

677. „Zu jung für alt“ – Vortrag in der Reihe „Science & Society“

Was tun, wenn das Berufsleben endet, man sich selbst aber viel zu jung fühlt, um zum alten Eisen zu gehören? Dieter Bednarz, über 30 Jahre SPIEGEL-Redakteur, kommt ins Grübeln, als ihm seine Firma

678. Postdoc Circle

Postdoc Representatives Konstantin Riege (Hoffmann Group) Danila Voronov (Cellerino Group) Yuliya Kurlishchuk (von Eyss Group) pdcc@leibniz-fli.de Postdoc Circle at FLI The Postdocs at the

679. Correia-Melo

Correia-Melo Research Group Host-Microbiome Metabolism in Aging Cells not only sense and take up nutrients from their surrounding environment, they also release a broad range of metabolites

680. Old and Healthy: Researchers Find Novel Genes for Longevity in Mammals

Fukomys damarensis (Source: Radim Sumbera/University Duisburg-Essen)

The genetic basis of lifespan determination is poorly understood. Most research has been done on short-lived animals, and it is unclear if these insights can be transferred to long-lived mammals like