Protein profiles and abundance
For our standard proteomic workflow, we use data independent acquisition (DIA) that enables us not only to identify, but also to compare abundancy changes of…
Protein-protein interactions
A simple way to analyze protein-protein interaction is the enrichment of a protein of interest with an antibody (immunoprecipitation) or a tag (e.g. GFP-trap) from…
Posttranslational modifications
Posttranslation modifications are important to understand the function of proteins as they can regulate activity, induce localisation changes and facilitate…
References
Bruderer, R. et al. Extending the limits of quantitative proteome profiling with data-independent acquisition and application to acetaminophen-treated three-dimensional liver…
Towards genomics of Nothobranchius furzeri
We have initiated projects to sequence a fraction of the N. furzeri genome by whole genome shotgun sequencing using Sanger and 454 sequencing technology.…
Technology
At the FLI, internal and external competencies are bundled in an efficient structure for technology transfer, thus following the BMBF-granted Leibniz-guidelines to implement and…
Prof. Dr. Sibyll Pollok erhält den diesjährigen Lehrpreis der Ernst-Abbe-Hochschule Jena. Mit diesem Preis würdigt die Hochschule das hohe Engagement und die außergewöhnlichen Lehrleistungen der…