von Eyss Research Group
Transcriptional control of tissue homeostasis: Lost in Transcription
The human body is composed of approximately 30 trillion cells and renews about four million cells per
Bierhoff Associated Research Group
Epigenetics of Aging
The group of Holger Bierhoff is associated to the FLI as a cooperation group between the Friedrich Schiller University Jena (FSU) and the FLI
Bierhoff Associated Research Group
Current Projects
Genome-wide approaches like high-throughput DNA- and RNA-sequencing have shown that only a small part of eukaryotic genomes codes for proteins
Contact
Jürgen Sühnel Coordinator JenAge +49 3641 65-6200 juergen.suehnel@leibniz-fli.de
Project Period: 01.10.2009 - 30.09.2014
JenAge (BMBF)
Aging and the development of age-related diseases are
Our lab focuses on HSCs and hematopoiesis in mice and humans and we use state-of-the art techniques to understand the effect of cell physiological processes on stem and progenitor cell function. We
The Aging Brain
Further, the group layed a strong research focus on neuro-immunological studies of NF-?B’s role in the injured and aged brain. Both NF-?B signaling pathways have important regulatory
We experimentally track the evolution of immune repertoires and microbes in killifish, a model organism of vertebrate aging. This project develops a predictive approach for the co-evolutionary
The ability to maintain a functional proteome declines during the aging process, which results in dysregulated protein homeostasis and the accumulation of damaged, misfolded, and partially
Wild mice vs laboratory mice
Also at FLI, mice are an important animal organism, e.g. in research on age-related processes such as muscle atrophy, colon cancer and stem cell aging. Mice in animal
Tetiana Poliezhaieva
Origin: I was born in Kharkiv (Charkow), the second largest city of Ukraine.
Position at FLI: I am a PhD candidate in Dr. Maria Ermolaeva group.
At FLI since: I joined FLI