Publications

2025

• Altered translation elongation contributes to key hallmarks of aging in the killifish brain.
  Di Fraia* D, Marino* A, Lee* JH, Kelmer Sacramento E, Baumgart M, Bagnoli S, Balla T, Schalk F, Kamrad S, Guan R, Caterino C, Giannuzzi C, Tomaz da Silva P, Sahu AK, Gut H, Siano G, Tiessen M, Terzibasi-Tozzini E, Fornasiero EF, Gagneur J, Englert C, Patil KR, Correia-Melo C, Nedialkova DD, Frydman** J, Cellerino** A, Ori** A
  Science 2025, 389(6759), eadk3079 * equal contribution, ** co-senior authors
  
• Wilms' tumor 1 impairs apoptotic clearance of fibroblasts in distal fibrotic lung lesions.
  Ediga HH, Vemulapalli CP, Sontake V, Patel PK, Miyazaki H, Popov D, Jensen MB, Jegga AG, Huang SK, Englert C, Schedl A, Gupta N, McCormack FX, Madala SK
  J Clin Invest 2025, 135(15), e188819
  
• Multiple Wnt signaling pathways direct epithelial tubule interconnection in the regenerating zebrafish kidney
  N.Kamei C, G.B.Sampson W, Albertz C, Aries O, Wolf A, M.Upadhyay R, M.Hughes S, Schenk H, Bonnet F, W.Draper B, W.McCracken K, K.Marciano D, Oxburgh L, A.Drummond I
  bioRxiv 2025, https://doi.org/10.1101/2025.03.
  
• The master male sex determinant Gdf6Y of the turquoise killifish arose through allelic neofunctionalization.
  Richter A, Mörl H, Thielemann M, Kleemann M, Geißen R, Schwarz R, Albertz C, Koch P, Petzold A, Kroll T, Groth M, Hartmann N, Herpin A, Englert C
  Nat Commun 2025, 16(1), 540
  

2024

• Single-cell sequencing analysis unravels genes/pathways regulating vertebrate aging
  Meng Y
  Dissertation 2024, Jena, Germany
  
• Sex chromosome turnover in African annual killifishes of the genus Nothobranchius
  Monika H, Pablo M, Anna CV, Ahmed AR, Sergey AS, Tomáš P, Marie A, Karolína J, Jana Š, Nikolas T, Marek J, Matyáš H, Liehr T, Martin R, Eugene YK, Petr R, Englert C, Petr N, Sember A
  bioRxiv 2024, https://doi.org/10.1101/2024.03.
  
• Hydra has mammal-like mutation rates facilitating fast adaptation despite its nonaging phenotype.
  Sahm A, Riege K, Groth M, Bens M, Kraus J, Fischer M, Kestler H, Englert C, Schaible R, Platzer M, Hoffmann S
  Genome Res 2024, 34(12), 2217-28
  
• UFMylation of CDK5RAP2/MCPH3 regulates mitosis
  Wu X
  Dissertation 2024, Jena, Germany
  

2023

• Establishing the auxin-inducible degron system for Wilms tumor protein 1 degradation in zebrafish
  Hopfenmüller V
  Dissertation 2023, Jena, Germany
  
• Generation of a transparent killifish line through multiplex CRISPR/Cas9mediated gene inactivation.
  Krug J, Perner B, Albertz C, Mörl H, Hopfenmüller VL, Englert C
  Elife 2023, 12, e81549