Publications

2025

• Prediction of resistance to hydroxyurea therapy in patients with polycythemia vera: a machine learning study (PV-AIM) validated in a prospective interventional phase IV trial (HU-F-AIM).
  Heidel* FH, De Stefano V, Zaiss M, Kisro J, Gückel E, Großer S, Zuurman MW, Manz K, Bryan K, Afsharinejad A, Griesshammer M, Kiladjian JJ
  Leukemia 2025, 39(7), 1692-701 * corresponding author
  
• Exploring the effects of amyloid beta (Aß) and Tau aggregation on neuronal activity and proteotoxicity in C. elegans
  Hirsch F
  Dissertation 2025, Bremen, Germany
  
• The transcriptome of the olm provides insights into its evolution and gene expression.
  Holtze S, Demirtürk D, Ohlenschläger O, Hegele S, Siniuk K, Förste S, Raghavan V, Groth M, Bens M, Hassel N, Martel A, Lukač M, Cizelj I, Fischer M, Liu H, Hildebrandt TB, Hoffmann S, Sahm A
  Sci Rep 2025, 15(1), 28324
  
• Multiple Origins of Sex Chromosomes in Nothobranchius Killifishes.
  Hospodářská M, Mora P, Voleníková AC, Al-Rikabi A, Altmanová M, Simanovsky SA, Tolar N, Pavlica T, Janečková K, Štundlová J, Bobryshava K, Jankásek M, Hiřman M, Liehr T, Reichard M, Krysanov EY, Ráb P, Englert C, Nguyen P, Sember A
  Mol Ecol 2025, 34(16), e70029
  
• Novel translational mouse models of metabolic dysfunction-associated steatotic liver disease comparable to human MASLD with severe obesity.
  Hupa-Breier KL, Schenk H, Campos-Murguia A, Wellhöner F, Heidrich B, Dywicki J, Hartleben B, Böker C, Mall J, Terkamp C, Wilkens L, Becker F, Rudolph KL, Manns MP, Mederacke YS, Marhenke S, Redeker H, Lieber M, Iordanidis K, Taubert R, Wedemeyer H, Noyan F, Hardtke-Wolenski M, Jaeckel E
  Mol Metab 2025, 93, 102104
  
• Cell-free DNA for detection and monitoring of extramedullary AML relapse.
  Hupe HC, Wienecke CP, Bartels S, Schipper E, Leßmann J, Lasch A, Bader M, Gabdoulline R, Neugebohren M, Dammann E, Kreipe HH, Lehmann U, Bergmann AK, Di Donato N, Stadler M, Eder M, Ganser A, Heidel FH, Thol F, Heuser M
  Hemasphere 2025, 9(3), e70097
  
• Fetal-like reversion in the regenerating intestine is regulated by mesenchymal asporin.
  Iqbal S, Andersson S, Nesta E, Pentinmikko N, Kumar A, Kumar Jha S, Borshagovski D, Webb A, Gebert N, Viitala EW, Ritchie A, Scharaw S, Kuuluvainen E, Larsen HL, Saarinen T, Juuti A, Ristimäki A, Jeltsch M, Ori A, Varjosalo M, Pietiläinen KH, Ollila S, Jensen KB, Oudhoff MJ, Katajisto P
  Cell Stem Cell 2025, 32(4), 613-626.e8
  
• Convergent evolution of a fungal effector enabling phagosome membrane penetration
  Jia LJ, Alexander Bernal F, Söhnlein J, Sonnberger J, Heineking I, Rafiq M, Cseresnyés Z, Kage F, Schmidt F, Zaher R, Hortschansky P, Chaudhary S, Gong X, Schirawski J, Thilo Figge M, Hube B, A.Brakhage A
  bioRxiv 2025, https://doi.org/10.1101/2025.03.
  
• RelB and C/EBPα critically regulate the development of Peyer's patch mononuclear phagocytes.
  Kanaya T, Jinnohara T, Sakakibara S, Tachibana N, Sasaki T, Kato T, Riemann M, Jin J, Shiroguchi K, Kawakami E, Ohno H
  Mucosal Immunol 2025, 18(1), 151-61
  
• The histone-methyltransferase DOT1L cooperates with LSD1 to control cell division in blast-phase MPN.
  Kapahnke K, Plenge T, Klaus T, Gupta MK, Anand D, Önder TT, Perner B, Schnöder TM, Thol FR, Damm F, Heidel FH, Perner F
  Leukemia 2025, 39(10), 2406-18