2024

  • Amyloid beta precursor protein contributes to brain aging and learning decline in short-lived turquoise killifish (Nothobranchius furzeri)
    E.M.de Bakker D, Mihaljević M, Gharat K, Richter Y, Bagnoli S, van Bebber F, Adam L, Shamim-Schulze F, Ohlenschläger O, Bens M, Cirri E, Antebi A, Matić I, Schneider A, Schmid B, Cellerino A, Kirstein J, Riccardo Valenzano D
    bioRxiv 2024, https://doi.org/10.1101/2024.10.
  • Denervation alters the secretome of myofibers and thereby affects muscle stem cell lineage progression and functionality.
    Henze H, Hüttner SS, Koch P, Schüler SC, Groth M, von Eyss B, von Maltzahn J
    NPJ Regen Med 2024, 9(1), 10
  • Acetylation-induced proteasomal degradation of the activated glucocorticoid receptor limits hormonal signaling.
    Iyer-Bierhoff A, Wieczorek M, Peter SM, Ward D, Bens M, Vettorazzi S, Guehrs KH, Tuckermann JP, Heinzel T
    iScience 2024, 27(2), 108943
  • Nonlinear DNA methylation trajectories in aging male mice.
    Olecka* M, van Bömmel* A, Best L, Haase M, Foerste S, Riege K, Dost T, Flor S, Witte OW, Franzenburg S, Groth M, von Eyss B, Kaleta C, Frahm C, Hoffmann S
    Nat Commun 2024, 15(1), 3074 * equal contribution
  • The Greenland shark (Somniosus microcephalus) genome provides insights into extreme longevity
    Sahm A, Cherkasov* A, Liu* H, Voronov D, Siniuk K, Schwarz R, Ohlenschlaeger O, Foerste S, Bens M, Groth M, Goerlich I, Paturej S, Klages S, Braendl B, Olsen J, Bushnell P, Bech Poulsen A, Ferrando S, Garibaldi F, Lorenzo Drago D, Terzibasi Tozzini E, Mueller FJ, Fischer M, Kretzmer H, Domenici** P, Fleng Steffensen** J, Cellerino** A, Hoffmann** S
    bioRxiv 2024, 10.1101/2024.09.09.611499 * equal contribution, ** co-corresponding authors
  • Hydra has mammal-like mutation rates facilitating fast adaptation despite its nonaging phenotype.
    Sahm A, Riege K, Groth M, Bens M, Kraus J, Fischer M, Kestler H, Englert C, Schaible R, Platzer M, Hoffmann S
    Genome Res 2024, 34(12), 2217-28
  • Tau mediates the reshaping of the transcriptional landscape toward intermediate Alzheimer's disease stages.
    Siano G, Varisco M, Terrigno M, Wang C, Scarlatti A, Iannone V, Groth M, Galas MC, Hoozemans JJM, Cellerino A, Cattaneo A, Di Primio C
    Front Cell Dev Biol 2024, 12, 1459573
  • The Neurobeachin-like 2 protein (NBEAL2) controls the homeostatic level of the ribosomal protein RPS6 in mast cells.
    Wegner P, Drube J, Ziegler L, Strotmann B, Marquardt R, Küchler C, Groth M, Nieswandt B, Andreas N, Drube S
    Immunology 2024, 172(1), 61-76
  • Repopulated microglia after pharmacological depletion decrease dendritic spine density in adult mouse brain.
    Wickel J, Chung HY, Ceanga M, von Stackelberg N, Hahn N, Candemir Ö, Baade-Büttner C, Mein N, Tomasini P, Woldeyesus DM, Andreas N, Baumgarten P, Koch P, Groth M, Wang ZQ, Geis C
    Glia 2024, 72(8), 1484-500
  • Ferritin heavy chain supports stability and function of the regulatory T cell lineage.
    Wu* Q, Carlos* AR, Braza* F, Bergman ML, Kitoko JZ, Bastos-Amador P, Cuadrado E, Martins R, Oliveira BS, Martins VC, Scicluna BP, Landry JJ, Jung FE, Ademolue TW, Peitzsch M, Almeida-Santos J, Thompson J, Cardoso S, Ventura P, Slot M, Rontogianni S, Ribeiro V, Domingues VDS, Cabral IA, Weis S, Groth M, Ameneiro C, Fidalgo M, Wang F, Demengeot J, Amsen D, Soares MP
    EMBO J 2024, 43(8), 1445-83