Rudolph Research Group



  • Cohesin-mediated NF-κB signaling limits hematopoietic stem cell self-renewal in aging and inflammation.
    Chen Z, Amro EM, Becker F, Hölzer M, Rasa SMM, Njeru SN, Han B, Di Sanzo S, Chen Y, Tang D, Tao S, Haenold R, Groth M, Romanov VS, Kirkpatrick JM, Kraus JM, Kestler HA, Marz M, Ori A, Neri F, Morita Y, Rudolph KL
    J Exp Med 2019, 216(1), 152-75


  • Metabolic Stress - Signaling and Metabolic Adaptation
    Balakrishnan P, Liebe T, Amro E, Dhaka L, Heinzel T, Heller R
    In: The Science of Hormesis in Health and Longevity (edited by Suresh ISR, Marios K) 2018, Academic Press, London
  • Cohesin deficiency enhances hematopoietic stem cell self-renewal in the context of aging and inflammation by impairing NK-ƙB induced differentiation
    Chen Z
    Dissertation 2018, Jena, Germany
  • Telomeric epigenetic response mediated by Gadd45a regulates stem cell aging and lifespan.
    Diao D, Wang H, Li T, Shi Z, Jin X, Sperka T, Zhu X, Zhang M, Yang F, Cong Y, Shen L, Zhan Q, Yan J, Song Z, Ju Z
    EMBO Rep 2018, 19(10), e45494
  • Cellular and epigenetic drivers of stem cell ageing.
    Ermolaeva** M, Neri** F, Ori** A, Rudolph** KL
    Nat Rev Mol Cell Biol 2018, 19(9), 594-610 ** co-corresponding authors
  • Telomeres in cancer.
    Gunes C, Avila AI, Rudolph KL
    Differentiation 2018, 99, 41-50
  • RelB regulates Th17 differentiation in a cell-intrinsic manner.
    Koliesnik IO, Andreas N, Romanov VS, Sreekantapuram S, Krljanac B, Haenold R, Weih F
    Immunobiology 2018, 223(2), 191-9
  • A Boolean network of the crosstalk between IGF and Wnt signaling in aging satellite cells.
    Siegle* L, Schwab* JD, Kühlwein* SD, Lausser L, Tümpel S, Pfister AS, Kühl** M, Kestler** HA
    PLoS One 2018, 13(3), e0195126 * equal contribution, ** co-senior authors
  • Senescence mirrors the extent of liver fibrosis in chronic hepatitis C virus infection.
    Wandrer F, Han B, Liebig S, Schlue J, Manns MP, Schulze-Osthoff K, Bantel H
    Aliment Pharmacol Ther 2018, 48(3), 270-80


  • Identification of novel Hox target genes with essential roles in hematopoietic stem cell self-renewal and differentiation
    Baig AH
    Dissertation 2017, Jena, Germany