Rudolph Research Group



  • Senescence and apoptosis block hematopoietic activation of quiescent hematopoietic stem cells with short telomeres.
    Wang J, Lu X, Sakk V, Klein CA, Rudolph KL
    Blood 2014, 124(22), 3237-40
  • Exonuclease 1 is essential for maintaining genomic stability and the proliferative capacity of neural but not hematopoietic stem cells.
    Zhang J, Yang R, Zhou D, Rudolph KL, Meng A, Ju Z
    Stem Cell Res 2014, 12(1), 250-9


  • Telomere stability--Wnt it or lose it.
    Bauer K, Tao S, Rudolph KL
    EMBO Rep 2013, 14(4), 297-8
  • Quantitative proteomic profiling of tumor cell response to telomere dysfunction using isotope-coded protein labeling (ICPL) reveals interaction network of candidate senescence markers.
    Biniossek ML, Lechel A, Rudolph KL, Martens UM, Zimmermann S
    J Proteomics 2013, 91, 515-35 published during change of institution
  • Grk5l Controls Heart Development by Limiting mTOR Signaling during Symmetry Breaking.
    Burkhalter MD, Fralish GB, Premont RT, Caron MG, Philipp M
    Cell Rep 2013, 4(4), 625-32
  • Are aging biomarkers clinically relevant in oncogeriatrics?
    Falandry C, Gilson E, Rudolph KL
    Crit Rev Oncol Hematol 2013, 85(3), 257-65 published during change of institution
  • The role of telomeres in stem cells and cancer.
    Günes C, Rudolph KL
    Cell 2013, 152(3), 390-3
  • CEBP factors regulate telomerase reverse transcriptase promoter activity in whey acidic protein-T mice during mammary carcinogenesis.
    Kumar M, Witt B, Knippschild U, Koch S, Meena JK, Heinlein C, Weise JM, Krepulat F, Kuchenbauer F, Iben S, Rudolph KL, Deppert W, Günes C
    Int J Cancer 2013, 132(9), 2032-43 published during change of institution
  • Loss of p53 in enterocytes generates an inflammatory microenvironment enabling invasion and lymph node metastasis of carcinogen-induced colorectal tumors.
    Schwitalla S, Ziegler PK, Horst D, Becker V, Kerle I, Begus-Nahrmann Y, Lechel A, Rudolph KL, Langer R, Slotta-Huspenina J, Bader FG, Prazeres da Costa O, Neurath MF, Meining A, Kirchner T, Greten FR
    Cancer Cell 2013, 23(1), 93-106 published during change of institution
  • Clonal analysis unveils self-renewing lineage-restricted progenitors generated directly from hematopoietic stem cells.
    Yamamoto* R, Morita* Y, Ooehara J, Hamanaka S, Onodera M, Rudolph KL, Ema H, Nakauchi H
    Cell 2013, 154(5), 1112-26 * equal contribution