Forschungsgruppe Valenzano

Ausgewählte Publikationen


  • Large-scale characterization of sex pheromone communication systems in Drosophila.
    Khallaf MA, Cui R, Weißflog J, Erdogmus M, Svatoš A, Dweck HKM, Valenzano DR, Hansson BS, Knaden M
    Nat Commun 2021, 12(1), 4165
  • Ancestral transoceanic colonization and recent population reduction in a nonannual killifish from the Seychelles archipelago.
    Cui R, Tyers AM, Malubhoy ZJ, Wisotsky S, Valdesalici S, Henriette E, Kosakovsky Pond SL, Valenzano DR
    Mol Ecol 2021, 30(14), 3610-23


  • Intra-species differences in population size shape life history and genome evolution.
    Willemsen D, Cui R, Reichard M, Valenzano DR
    Elife 2020, 9
  • Antibody repertoire sequencing reveals systemic and mucosal immunosenescence in the short-lived turquoise killifish
    Bradshaw WJ, Poeschla M, Placzek A, Valenzano DR
    bioRxiv 2020,
  • Extreme genomic volatility characterizes the evolution of the immunoglobulin heavy chain locus in cyprinodontiform fishes.
    Bradshaw WJ, Valenzano DR
    Proc Biol Sci 2020, 287(1927), 20200489


  • Relaxed Selection Limits Lifespan by Increasing Mutation Load.
    Cui R, Medeiros T, Willemsen D, Iasi LNM, Collier GE, Graef M, Reichard M, Valenzano DR
    Cell 2019, 178(2), 385-399.e20
  • Loss of genomic integrity induced by lysosphingolipid imbalance drives ageing in the heart.
    Ahuja G, Bartsch D, Yao W, Geissen S, Frank S, Aguirre A, Russ N, Messling JE, Dodzian J, Lagerborg KA, Vargas NE, Muck JS, Brodesser S, Baldus S, Sachinidis A, Hescheler J, Dieterich C, Trifunovic A, Papantonis A, Petrascheck M, Klinke A, Jain M, Valenzano** DR, Kurian** L
    EMBO Rep 2019, 20(4) ** co-corresponding authors


  • Regulation of life span by the gut microbiota in the short-lived African turquoise killifish.
    Smith P, Willemsen D, Popkes M, Metge F, Gandiwa E, Reichard M, Valenzano DR
    Elife 2017, 6


  • Efficient genome engineering approaches for the short-lived African turquoise killifish.
    Harel I, Valenzano DR, Brunet A
    Nat Protoc 2016, 11(10), 2010-28


  • The African Turquoise Killifish Genome Provides Insights into Evolution and Genetic Architecture of Lifespan.
    Valenzano DR, Benayoun BA, Singh PP, Zhang E, Etter PD, Hu CK, Clément-Ziza M, Willemsen D, Cui R, Harel I, Machado BE, Yee MC, Sharp SC, Bustamante CD, Beyer A, Johnson EA, Brunet A
    Cell 2015, 163(6), 1539-54