Publikationen

2021

• Nbs1-mediated DNA damage repair pathway regulates haematopoietic stem cell development and embryonic haematopoiesis.
  Chen Y, Sun J, Ju Z, Wang ZQ, Li T
  Cell Prolif 2021 (epub ahead of print)
  
• The Role of the Pathogen Dose and PI3Kγ in Immunometabolic Reprogramming of Microglia for Innate Immune Memory.
  Lajqi T, Marx C, Hudalla H, Haas F, Große S, Wang ZQ, Heller R, Bauer M, Wetzker R, Bauer R
  Int J Mol Sci 2021, 22(5)
  
• The N-terminal BRCT domain determines MCPH1 function in brain development and fertility.
  Liu* X, Schneble-Löhnert* N, Kristofova M, Qing X, Labisch J, Hofmann S, Ehrenberg S, Sannai M, Jörß T, Ori A, Godmann M, Wang ZQ
  Cell Death Dis 2021, 12(2), 143 * equal contribution
  
• Cooperative treatment effectiveness of ATR and HSP90 inhibition in Ewing's sarcoma cells
  Marx C, Schaarschmidt MU, Kirkpatrick J, Marx-Blümel L, Halilovic M, Westermann M, Hoelzer D, Meyer FB, Geng Y, Buder K, Schadwinkel HM, Siniuk K, Becker S, Thierbach R, Beck JF, Sonnemann* J, Wang* ZQ
  Cell Biosci 2021, 11(1), 57 * equal contribution
  
• HAT cofactor TRRAP modulates microtubule dynamics via SP1 signaling to prevent neurodegeneration.
  Tapias* A, Lázaro* D, Yin* BK, Rasa SMM, Krepelova A, Kelmer Sacramento E, Grigaravicius P, Koch P, Kirkpatrick J, Ori A, Neri F, Wang ZQ
  Elife 2021 (epub ahead of print) * equal contribution
  

2020

• Mapping sites of carboxymethyllysine modification on proteins reveals its consequences for proteostasis and cell proliferation
  Di Sanzo* S, Spengler* K, Leheis A, Kirkpatrick JM, Rändler TL, Baldensperger T, Parca L, Marx C, Wang ZQ, Glomb A, Ori** A, Heller** R
  bioRxiv 2020, https://doi.org/10.1101/2020.10. * equal contribution, ** co-senior authors, ** co-corresponding authors
  
• Bi-allelic HPDL Variants Cause a Neurodegenerative Disease Ranging from Neonatal Encephalopathy to Adolescent-Onset Spastic Paraplegia.
  Husain RA, Grimmel M, Wagner M, Hennings JC, Marx C, Feichtinger RG, Saadi A, Rostásy K, Radelfahr F, Bevot A, Döbler-Neumann M, Hartmann H, Colleaux L, Cordts I, Kobeleva X, Darvish H, Bakhtiari S, Kruer MC, Besse A, Ng ACH, Chiang D, Bolduc F, Tafakhori A, Mane S, Ghasemi Firouzabadi S, Huebner AK, Buchert R, Beck-Woedl S, Müller AJ, Laugwitz L, Nägele T, Wang ZQ, Strom TM, Sturm M, Meitinger T, Klockgether T, Riess O, Klopstock T, Brandl U, Hübner CA, Deschauer M, Mayr JA, Bonnen PE, Krägeloh-Mann I, Wortmann SB, Haack TB
  Am J Hum Genet 2020, 107(2), 364-73
  
• Cell Metabolic Alterations due to Mcph1 Mutation in Microcephaly.
  Journiac N, Gilabert-Juan J, Cipriani S, Benit P, Liu X, Jacquier S, Faivre V, Delahaye-Duriez A, Csaba Z, Hourcade T, Melinte E, Lebon S, Violle-Poirsier C, Oury JF, Adle-Biassette H, Wang ZQ, Mani S, Rustin P, Gressens P, Nardelli J
  Cell Rep 2020, 31(2), 107506
  
• ATR is essential for preservation of cell mechanics and nuclear integrity during interstitial migration.
  Kidiyoor GR, Li Q, Bastianello G, Bruhn C, Giovannetti I, Mohamood A, Beznoussenko GV, Mironov A, Raab M, Piel M, Restuccia U, Matafora V, Bachi A, Barozzi S, Parazzoli D, Frittoli E, Palamidessi A, Panciera T, Piccolo S, Scita G, Maiuri P, Havas KM, Zhou ZW, Kumar A, Bartek J, Wang ZQ, Foiani M
  Nat Commun 2020, 11(1), 4828
  
• Biomimetic reconstruction of the hematopoietic stem cell niche for in vitro amplification of human hematopoietic stem cells.
  Marx-Blümel L, Marx C, Weise F, Frey J, Perner B, Schlingloff G, Lindig N, Hampl J, Sonnemann J, Brauer D, Voigt A, Singh S, Beck B, Jäger UM, Wang ZQ, Beck JF, Schober A
  PLoS One 2020, 15(6), e0234638