Forschungsgruppe von Eyss

Ausgewählte Publikationen

  • TRPS1 shapes YAP/TEAD-dependent transcription in breast cancer cells.
    Elster* D, Tollot* M, Schlegelmilch K, Ori A, Rosenwald A, Sahai E, von Eyss B
    Nat Commun 2018, 9(1), 3115 * equal contribution
  • Ubiquitin-Dependent Turnover of MYC Antagonizes MYC/PAF1C Complex Accumulation to Drive Transcriptional Elongation.
    Jaenicke* LA, von Eyss* B, Carstensen A, Wolf E, Xu W, Greifenberg AK, Geyer M, Eilers M, Popov N
    Mol Cell 2016, 61(1), 54-67 * equal contribution
  • Repression of SRF target genes is critical for Myc-dependent apoptosis of epithelial cells.
    Wiese* KE, Haikala* HM, von Eyss* B, Wolf E, Esnault C, Rosenwald A, Treisman R, Klefström J, Eilers M
    EMBO J 2015, 34(11), 1554-71 * equal contribution
  • A MYC-Driven Change in Mitochondrial Dynamics Limits YAP/TAZ Function in Mammary Epithelial Cells and Breast Cancer.
    von Eyss B, Jaenicke LA, Kortlever RM, Royla N, Wiese KE, Letschert S, McDuffus LA, Sauer M, Rosenwald A, Evan GI, Kempa S, Eilers M
    Cancer Cell 2015, 28(6), 743-57
  • The SNF2-like helicase HELLS mediates E2F3-dependent transcription and cellular transformation.
    von Eyss B, Maaskola J, Memczak S, Möllmann K, Schuetz A, Loddenkemper C, Tanh MD, Otto A, Muegge K, Heinemann U, Rajewsky N, Ziebold U
    EMBO J 2012, 31(4), 972-85
  • The human synMuv-like protein LIN-9 is required for transcription of G2/M genes and for entry into mitosis.
    Osterloh* L, von Eyss* B, Schmit F, Rein L, Hübner D, Samans B, Hauser S, Gaubatz S
    EMBO J 2007, 26(1), 144-57 * equal contribution

Publikationen am FLI

2021

  • High Yap and Mll1 promote a persistent regenerative cell state induced by Notch signaling and loss of p53.
    Heuberger J, Grinat J, Kosel F, Liu L, Kunz S, Vidal RO, Keil M, Haybaeck J, Robine S, Louvard D, Regenbrecht C, Sporbert A, Sauer S, von Eyss B, Sigal M, Birchmeier W
    Proc Natl Acad Sci U S A 2021, 118(22)
  • PLCG1 is required for AML1-ETO leukemia stem cell self-renewal.
    Schnoeder TM, Schwarzer A, Jayavelu AK, Hsu CJ, Kirkpatrick J, Döhner K, Perner F, Eifert T, Huber N, Arreba-Tutusaus P, Dolnik A, Assi SA, Nafria M, Jiang L, Dai YT, Chen Z, Chen SJ, Kellaway SG, Ptasinska A, Ng ES, Stanley EG, Elefanty AG, Buschbeck M, Bierhoff H, Brodt S, Matziolis G, Fischer KD, Hochhaus A, Chen CW, Heidenreich O, Mann M, Lane SW, Bullinger L, Ori A, Eyss Bv, Bonifer C, Heidel F
    Blood 2021 (epub ahead of print)
  • A comprehensive transcriptome signature of murine hematopoietic stem cell aging.
    Svendsen AF, Yang D, Kim KM, Lazare SS, Skinder N, Zwart E, Mura-Meszaros A, Ausema A, Eyss Bv, de Haan G, Bystrykh LV
    Blood 2021, 138(6), 439-51

2020

  • Control mechanisms of YAP activity
    Elster D
    Dissertation 2020, Jena, Germany
  • Hippo Signaling in Regeneration and Aging.
    Elster D, von Eyss B
    Mech Ageing Dev 2020, 189, 111280
  • The role of Hippo signaling in hematopoietic stem cell aging
    Mura-Mészáros A
    Dissertation 2020, Jena, Germany
  • Der Hippo-Signalweg in der Regeneration und im Krebs
    Tollot M, Cindric Vranesic A, von Eyss B
    BIOspektrum 2020, 26, 154–157

2019

  • Publisher Correction: Pharmacological reactivation of MYC-dependent apoptosis induces susceptibility to anti-PD-1 immunotherapy.
    Haikala HM, Anttila JM, Marques E, Raatikainen T, Ilander M, Hakanen H, Ala-Hongisto H, Savelius M, Balboa D, Von Eyss B, Eskelinen V, Munne P, Nieminen AI, Otonkoski T, Schüler J, Laajala TD, Aittokallio T, Sihto H, Mattson J, Heikkilä P, Leidenius M, Joensuu H, Mustjoki S, Kovanen P, Eilers M, Leverson JD, Klefström J
    Nat Commun 2019, 10(1), 932
  • Pharmacological reactivation of MYC-dependent apoptosis induces susceptibility to anti-PD-1 immunotherapy.
    Haikala HM, Anttila JM, Marques E, Raatikainen T, Ilander M, Hakanen H, Ala-Hongisto H, Savelius M, Balboa D, Von Eyss B, Eskelinen V, Munne P, Nieminen AI, Otonkoski T, Schüler J, Laajala TD, Aittokallio T, Sihto H, Mattson J, Heikkilä P, Leidenius M, Joensuu H, Mustjoki S, Kovanen P, Eilers M, Leverson JD, Klefström J
    Nat Commun 2019, 10(1), 620
  • The Myb-MuvB Complex Is Required for YAP-Dependent Transcription of Mitotic Genes.
    Pattschull G, Walz S, Gründl M, Schwab M, Rühl E, Baluapuri A, Cindric-Vranesic A, Kneitz S, Wolf E, Ade CP, Rosenwald A, von Eyss B, Gaubatz S
    Cell Rep 2019, 27(12), 3533-3546.e7