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Forschungsgruppe Ori

Publikationen

2023

  • A comprehensive atlas of the aging vertebrate brain reveals signatures of progressive proteostasis dysfunction
    Di Fraia* D, Marino* A, Ho Lee* J, Kelmer Sacramento E, Baumgart M, Bagnoli S, Tomaz da Silva P, Kumar Sahu A, Siano G, Tiessen M, Terzibasi-Tozzini E, Gagneur J, Frydman** J, Cellerino** A, Ori** A
    bioRxiv 2023, 10.1101/2023.07.20.549210 * equal contribution, ** co-corresponding authors
  • Impact of Hypermannosylation on the Structure and Functionality of the ER and the Golgi Complex.
    Franzka P, Schüler SC, Kentache T, Storm R, Bock A, Katona I, Weis J, Buder K, Kaether C, Hübner CA
    Biomedicines 2023, 11(1), 146.doi: 10.3390/biomedicines110
  • Impact of inflammatory preconditioning on murine microglial proteome response induced by focal ischemic brain injury
    Helbing DL, Haas F, Cirri E, Rahnis N, Thuy Dung Dau T, Kelmer Sacramento E, Oraha N, Böhm L, Morrison H, Bauer R
    bioRxiv 2023, 10.1101/2023.04.13.536755
  • Membrane shapers from two distinct superfamilies cooperate in the development of neuronal morphology.
    Izadi M, Wolf D, Seemann E, Ori A, Schwintzer L, Steiniger F, Kessels MM, Qualmann B
    J Cell Biol 2023, 222(8)
  • Metabololipidomic and proteomic profiling reveals aberrant macrophage activation and interrelated immunomodulatory mediator release during aging.
    Schädel P, Czapka A, Gebert N, Jacobsen ID, Ori** A, Werz** O
    Aging Cell 2023, 22(7), e13856 ** co-corresponding authors
  • Short-Term Caloric Restriction and Subsequent Re-Feeding Compromise Liver Health and Associated Lipid Mediator Signaling in Aged Mice.
    Schädel P, Wichmann-Costaganna M, Czapka A, Gebert N, Ori A, Werz O
    Nutrients 2023, 15(16), 3660
  • Mis-spliced transcripts generate de novo proteins in TDP-43-related ALS/FTD.
    Seddighi S, Qi YA, Brown AL, Wilkins OG, Bereda C, Belair C, Zhang Y, Prudencio M, Keuss MJ, Khandeshi A, Pickles S, Hill SE, Hawrot J, Ramos DM, Yuan H, Roberts J, Sacramento EK, Shah SI, Nalls MA, Colon-Mercado J, Reyes JF, Ryan VH, Nelson MP, Cook C, Li Z, Screven L, Kwan JY, Shantaraman A, Ping L, Koike Y, Oskarsson BR, Staff N, Duong DM, Ahmed A, Secrier M, Ule J, Jacobson S, Rohrer J, Malaspina A, Glass JD, Ori A, Seyfried NT, Maragkakis M, Petrucelli L, Fratta P, Ward ME
    bioRxiv 2023

2022

  • Investigating the proteasome interaction network using proximity ligation coupled to mass spectrometry
    Bartolome A
    Dissertation 2022, Jena, Germany
  • ProteasomeID: quantitative mapping of proteasome interactomes and substrates for in vitro and in vivo studies
    Bartolome A, Heiby* JC, Dau* T, Di Fraia D, Heinze I, Kirkpatrick JM, Ori A
    bioRxiv 2022, https://doi.org/10.1101/2022.08. * equal contribution
  • Human NMDAR autoantibodies disrupt excitatory-inhibitory balance leading to hippocampal network hypersynchrony
    Ceanga M, Rahmati V, Haselmann H, Schmidl L, Hunter D, Kreye J, Prüss H, Groc L, Hallermann S, Dalmau J, Ori A, Heckmann M, Geis C
    bioRxiv 2022, https://doi.org/10.1101/2022.03.