Publikationen

2025

• The microcephaly-associated protein YIPF5 differentially regulates ER-export
  Bruno F, Anitei M, Di Fraia D, Durso W, Dau T, Cirri E, Sannai M, Valkova C, Maldutyte J, A.Miller E, Rubio I, Garloff V, Kersten N, Farias G, Ori A, Mestres I, Calegari F, Kaether C
  bioRxiv 2025, https://doi.org/10.1101/2025.06.
  
• Fetal-like reversion in the regenerating intestine is regulated by mesenchymal asporin.
  Iqbal S, Andersson S, Nesta E, Pentinmikko N, Kumar A, Kumar Jha S, Borshagovski D, Webb A, Gebert N, Viitala EW, Ritchie A, Scharaw S, Kuuluvainen E, Larsen HL, Saarinen T, Juuti A, Ristimäki A, Jeltsch M, Ori A, Varjosalo M, Pietiläinen KH, Ollila S, Jensen KB, Oudhoff MJ, Katajisto P
  Cell Stem Cell 2025, 32(4), 613-626.e8
  
• Lonafarnib Partially Reverses Cardiac Senescence in Human and Mouse Progeria Models via Autophagy Activation
  M.Monteiro L, R.Pitrez P, Correia-Santos S, Dark N, Santinha D, Aveleira C, Townsend M, Taylor J, Nissan X, Sardão V, Cortes L, Mitter R, Marino A, Sousa-Soares C, Ribeiro R, C.Smith J, Logarinho E, Ori A, S.Bernardo A, Ferreira L
  bioRxiv 2025, https://doi.org/10.1101/2025.06.
  
• iSODA: A Comprehensive Tool for Integrative Omics Data Analysis in Single- and Multi-Omics Experiments.
  Olivier-Jimenez D, Derks RJE, Harari O, Cruchaga C, Ali M, Ori A, Di Fraia D, Cabukusta B, Henrie A, Giera M, Mohammed Y
  Anal Chem 2025 (epub ahead of print)
  

2024

• Quantitative mapping of proteasome interactomes and substrates using ProteasomeID.
  Bartolome A, Heiby* JC, Di Fraia* D, Heinze I, Knaudt H, Spaeth E, Omrani O, Minetti A, Hofmann M, Kirkpatrick JM, Dau** T, Ori** A
  Elife 2024, 13, RP93256 * equal contribution, ** co-corresponding authors
  
• NRF2 activation by cysteine as a survival mechanism for triple-negative breast cancer cells.
  Bottoni L, Minetti A, Realini G, Pio E, Giustarini D, Rossi R, Rocchio C, Franci L, Salvini L, Catona O, D'Aurizio R, Rasa M, Giurisato E, Neri F, Orlandini M, Chiariello M, Galvagni F
  Oncogene 2024, 43(22), 1701-13
  
• The Aging Synapse: An Integrated Proteomic And Transcriptomic Analysis
  Caterino* C, Ugolini* M, Durso W, Jevdokimenko K, Groth M, Riege K, Görlach M, Fornasiero E, Ori A, Hoffmann S, Cellerino A
  bioRxiv 2024, https://doi.org/10.1101/2024.12. * equal contribution
  
• Optimized Automated Workflow for BioID Improves Reproducibility and Identification of Protein-Protein Interactions.
  Cirri E, Knaudt H, Di Fraia D, Pömpner N, Rahnis N, Heinze I, Ori** A, Dau** T
  J Proteome Res 2024, 23(10), 4359-68 ** co-corresponding authors
  
• The Neurolipid Atlas: a lipidomics resource for neurodegenerative diseases uncovers cholesterol as a regulator of astrocyte reactivity impaired by ApoE4
  Feringa FM, Koppes-den Hertog SJ, Wang L, Derks RJE, Kruijff I, Erlebach L, Heijneman J, Miramontes R, Pömpner N, Blomberg N, Olivier-Jimenez D, Eva Johansen L, Cammack AJ, Giblin A, Toomey CE, Rose IVL, Yuan H, Ward M, Isaacs AM, Kampmann M, Kronenberg-Versteeg D, Lashley T, M.Thompson L, Ori A, Mohammed Y, Giera M, van der Kant R
  bioRxiv 2024, https://doi.org/10.1101/2024.07.
  
• Cell-Type Resolved Protein Atlas of Brain Lysosomes Identifies SLC45A1-Associated Disease as a Lysosomal Disorder.
  Ghoochani A, Heiby JC, Rawat ES, Medoh UN, Di Fraia D, Dong W, Gastou M, Nyame K, Laqtom NN, Gomez-Ospina N, Ori A, Abu-Remaileh M
  bioRxiv 2024, 10.1101/2024.10.14.618295