Publikationen Projekt Biochemie
2023
- ABRAXAS1 orchestrates BRCA1 activities to counter genome destabilizing repair pathways-lessons from breast cancer patients.
Sachsenweger J, Jansche R, Merk T, Heitmeir B, Deniz M, Faust U, Roggia C, Tzschach A, Schroeder C, Riess A, Pospiech H, Peltoketo H, Pylkäs K, Winqvist R, Wiesmüller L
Cell Death Dis 2023, 14(5), 328
2022
- Partial Reduction in BRCA1 Gene Dose Modulates DNA Replication Stress Level and Thereby Contributes to Sensitivity or Resistance.
Classen S, Rahlf E, Jungwirth J, Albers N, Hebestreit LP, Zielinski A, Poole L, Groth M, Koch P, Liehr T, Kankel S, Cordes N, Petersen C, Rothkamm K, Pospiech** H, Borgmann** K
Int J Mol Sci 2022, 23(21) ** co-corresponding authors - Charakterisierung des potentiellen DNA-Replikationsfaktors PN70
Kutz J
Dissertation 2022, Jena, Germany
2021
- Molekularbiologische Beschreibung des Alterungsprozesses
Diekmann S, Grosse F, Hemmerich P, Pospiech H
In: Handbuch Alter und Altern, J.B. Metzler (edited by Fuchs M) 2021, 145–151, Springer, Heidelberg
2020
- Multiple biochemical properties of the p53 molecule contribute to activation of polymerase iota-dependent DNA damage tolerance.
Biber S, Pospiech H, Gottifredi V, Wiesmüller L
Nucleic Acids Res 2020, 48(21), 12188-203
2019
- In vivo Study of Human DHX9 Helicase Functions
Aly YSH
Dissertation 2019, Jena, Germany - BRCA1 mislocalization leads to aberrant DNA damage response in heterozygous ABRAXAS1 mutation carrier cells.
Bose M, Sachsenweger J, Laurila N, Parplys AC, Willmann J, Jungwirth J, Groth M, Rapakko K, Nieminen P, Friedl TWP, Heiserich L, Meyer F, Tuppurainen H, Peltoketo H, Nevanlinna H, Pylkäs K, Borgmann K, Wiesmüller L, Winqvist** R, Pospiech** H
Hum Mol Genet 2019, 28(24), 4148-60 ** co-corresponding authors - Local inhibition of rRNA transcription without nucleolar segregation after targeted ion irradiation of the nucleolus.
Siebenwirth C, Greubel C, Drexler GA, Reindl J, Walsh DWM, Schwarz B, Sammer M, Baur I, Pospiech H, Schmid TE, Dollinger G, Friedl AA
J Cell Sci 2019, 132(19), jcs232181
2018
- The ATR-Activation Domain of TopBP1 Is Required for the Suppression of Origin Firing during the S Phase.
Sokka* M, Koalick* D, Hemmerich P, Syväoja JE, Pospiech H
Int J Mol Sci 2018, 19(8) * equal contribution
