Publikationen

2025

• Novel translational mouse models of metabolic dysfunction-associated steatotic liver disease comparable to human MASLD with severe obesity.
  Hupa-Breier KL, Schenk H, Campos-Murguia A, Wellhöner F, Heidrich B, Dywicki J, Hartleben B, Böker C, Mall J, Terkamp C, Wilkens L, Becker F, Rudolph KL, Manns MP, Mederacke YS, Marhenke S, Redeker H, Lieber M, Iordanidis K, Taubert R, Wedemeyer H, Noyan F, Hardtke-Wolenski M, Jaeckel E
  Mol Metab 2025 (epub ahead of print)
  
• Cell-free DNA for detection and monitoring of extramedullary AML relapse.
  Hupe HC, Wienecke CP, Bartels S, Schipper E, Leßmann J, Lasch A, Bader M, Gabdoulline R, Neugebohren M, Dammann E, Kreipe HH, Lehmann U, Bergmann AK, Di Donato N, Stadler M, Eder M, Ganser A, Heidel FH, Thol F, Heuser M
  Hemasphere 2025, 9(3), e70097
  
• Fetal-like reversion in the regenerating intestine is regulated by mesenchymal asporin.
  Iqbal S, Andersson S, Nesta E, Pentinmikko N, Kumar A, Kumar Jha S, Borshagovski D, Webb A, Gebert N, Viitala EW, Ritchie A, Scharaw S, Kuuluvainen E, Larsen HL, Saarinen T, Juuti A, Ristimäki A, Jeltsch M, Ori A, Varjosalo M, Pietiläinen KH, Ollila S, Jensen KB, Oudhoff MJ, Katajisto P
  Cell Stem Cell 2025, 32(4), 613-626.e8
  
• Neuronal autophagy in the control of synapse function.
  Karpova A, Hiesinger PR, Kuijpers M, Albrecht A, Kirstein J, Andres-Alonso M, Biermeier A, Eickholt BJ, Mikhaylova M, Maglione M, Montenegro-Venegas C, Sigrist SJ, Gundelfinger ED, Haucke V, Kreutz MR
  Neuron 2025, 113(7), 974-90
  
• The evolving landscape of epigenetic target molecules and therapies in myeloid cancers: focus on acute myeloid leukemia and myeloproliferative neoplasms.
  Kühn MWM, Pemmaraju N, Heidel FH
  Leukemia 2025 (epub ahead of print)
  
• Pathogenesis and management of high molecular risk myeloproliferative neoplasms.
  Ling VY, Heidel FH, Bywater MJ
  Haematologica 2025, 110(4), 863-76
  
• Oncogenic FLT3 internal tandem duplications (ITD) and CD45/PTPRC control osteoclast functions and bone microarchitecture.
  Lossius-Cott C, Annoh A, Bens M, Nietzsche S, Hoffmann B, Figge MT, Rauner M, Hofbauer LC, Müller JP
  JBMR Plus 2025, 9(3), ziae173
  
• Lonafarnib Partially Reverses Cardiac Senescence in Human and Mouse Progeria Models via Autophagy Activation
  M.Monteiro L, R.Pitrez P, Correia-Santos S, Dark N, Santinha D, Aveleira C, Townsend M, Taylor J, Nissan X, Sardão V, Cortes L, Mitter R, Marino A, Sousa-Soares C, Ribeiro R, C.Smith J, Logarinho E, Ori A, S.Bernardo A, Ferreira L
  bioRxiv 2025, https://doi.org/10.1101/2025.06.
  
• DNA damage response regulator ATR licenses PINK1-mediated mitophagy.
  Marx* C, Qing* X, Gong* Y, Kirkpatrick J, Siniuk K, Beznoussenko GV, Kidiyoor GR, Kirtay M, Buder K, Koch P, Westermann M, Bruhn C, Brown EJ, Xu X, Foiani M, Wang ZQ
  Nucleic Acids Res 2025, 53(5), gkaf178 * equal contribution
  
• Infection and herbicide exposure implicate c-Abl kinase in α-Synuclein Ser129 phosphorylation
  Marzieh E, Zeyang S, Alvaro QO, Gesa R, Mahdi R, David H, Saskia FE, Thomas FM
  bioRxiv 2025, https://doi.org/10.1101/2025.01.