Publikationen

2025

• Function of the anti-aging protein Klotho in the Choroid plexus
  Fanaeikahrani Z
  Dissertation 2025, Jena, Germany
  
• p53 reveals principles of chromatin remodeling and enhancer activation.
  Fischer M, Schwarz* R, Riege* K, Förste S, Schwab K, Wiechens E, van Bömmel A, Hoffmann S
  Nucleic Acids Res 2025, 53(11), gkaf465 * equal contribution
  
• Microglia and CD8+ T cell activation precede neuronal loss in a murine model of spastic paraplegia 15.
  Frolov A, Huang H, Schütz D, Köhne M, Blank-Stein N, Osei-Sarpong C, Büttner M, Elmzzahi T, Khundadze M, Zahid M, Reuter M, Becker M, De Domenico E, Bonaguro L, Kallies A, Morrison H, Hübner CA, Händler K, Stumm R, Mass E, Beyer MD
  J Exp Med 2025, 222(7), e20232357
  
• Subtyping Burkitt Lymphoma by DNA Methylation.
  Glaser S, Wagener R, Kretzmer H, López C, Baptista MJ, Bens S, Bernhart S, Bhatia K, Borkhardt A, Elgaafary S, Hoffmann S, Hübschmann D, Hummel M, Klapper W, Kolarova J, Kreuz M, Lazzi S, Löffler M, Navarro JT, Neequaye J, Onyango N, Onyuma T, Ott G, Radlwimmer B, Rohde M, Rosenwald A, Rosolowski M, Schlesner M, Szczepanowski M, Tapia G, Wößmann W, Küppers R, Trümper L, Leoncini L, Lichter P, Del Val C, Ammerpohl O, Burkhardt B, Mbulaiteye SM, Siebert R, ICGC MMML‐Seq Consortium MMML Project
  Genes Chromosomes Cancer 2025, 64(4), e70042
  
• Attenuated growth factor signaling during cell death initiation sensitizes membranes towards peroxidation.
  Gollowitzer A, Pein H, Rao Z, Waltl L, Bereuter L, Loeser K, Meyer T, Jafari V, Witt F, Winkler R, Su F, Große S, Thürmer M, Grander J, Hotze M, Harder S, Espada L, Magnutzki A, Gstir R, Weinigel C, Rummler S, Bonn G, Pachmayr J, Ermolaeva M, Harayama T, Schlüter H, Kosan C, Heller R, Thedieck K, Schmitt M, Shimizu T, Popp J, Shindou H, Kwiatkowski M, Koeberle A
  Nat Commun 2025, 16(1), 1774
  
• How I diagnose and treat patients in the pre-fibrotic phase of primary myelofibrosis (pre-PMF) - practical approaches of a German expert panel discussion in 2024.
  Griesshammer M, Al-Ali HK, Eckardt JN, Fiegl M, Göthert J, Jentsch-Ullrich K, Koschmieder S, Kvasnicka HM, Reiter A, Schmidt B, Heidel FH
  Ann Hematol 2025, 104(1), 295-306
  
• Prediction of resistance to hydroxyurea therapy in patients with polycythemia vera: a machine learning study (PV-AIM) validated in a prospective interventional phase IV trial (HU-F-AIM).
  Heidel* FH, De Stefano V, Zaiss M, Kisro J, Gückel E, Großer S, Zuurman MW, Manz K, Bryan K, Afsharinejad A, Griesshammer M, Kiladjian JJ
  Leukemia 2025, 39(7), 1692-701 * corresponding author
  
• Novel translational mouse models of metabolic dysfunction-associated steatotic liver disease comparable to human MASLD with severe obesity.
  Hupa-Breier KL, Schenk H, Campos-Murguia A, Wellhöner F, Heidrich B, Dywicki J, Hartleben B, Böker C, Mall J, Terkamp C, Wilkens L, Becker F, Rudolph KL, Manns MP, Mederacke YS, Marhenke S, Redeker H, Lieber M, Iordanidis K, Taubert R, Wedemeyer H, Noyan F, Hardtke-Wolenski M, Jaeckel E
  Mol Metab 2025, 93, 102104
  
• Cell-free DNA for detection and monitoring of extramedullary AML relapse.
  Hupe HC, Wienecke CP, Bartels S, Schipper E, Leßmann J, Lasch A, Bader M, Gabdoulline R, Neugebohren M, Dammann E, Kreipe HH, Lehmann U, Bergmann AK, Di Donato N, Stadler M, Eder M, Ganser A, Heidel FH, Thol F, Heuser M
  Hemasphere 2025, 9(3), e70097
  
• Fetal-like reversion in the regenerating intestine is regulated by mesenchymal asporin.
  Iqbal S, Andersson S, Nesta E, Pentinmikko N, Kumar A, Kumar Jha S, Borshagovski D, Webb A, Gebert N, Viitala EW, Ritchie A, Scharaw S, Kuuluvainen E, Larsen HL, Saarinen T, Juuti A, Ristimäki A, Jeltsch M, Ori A, Varjosalo M, Pietiläinen KH, Ollila S, Jensen KB, Oudhoff MJ, Katajisto P
  Cell Stem Cell 2025, 32(4), 613-626.e8