Publikationen

2018

• LSD1 (KDM1A)-independent effects of the LSD1 inhibitor SP2509 in cancer cells.
  Sonnemann J, Zimmermann M, Marx C, Ebert F, Becker S, Lauterjung ML, Beck JF
  Br J Haematol 2018, 183(4), 494-7
  

2017

• XRCC1 mutation is associated with PARP1 hyperactivation and cerebellar ataxia.
  Hoch NC, Hanzlikova H, Rulten SL, Tétreault M, Komulainen E, Ju L, Hornyak P, Zeng Z, Gittens W, Rey SA, Staras K, Mancini GMS, McKinnon PJ, Wang ZQ, Wagner JD, Care4Rare Canada Consortium, Yoon G, Caldecott KW
  Nature 2017, 541(7635), 87-91
  
• PARP1 controls KLF4-mediated telomerase expression in stem cells and cancer cells.
  Hsieh MH, Chen YT, Chen YT, Lee YH, Lu J, Chien CL, Chen HF, Ho HN, Yu CJ, Wang ZQ, Teng SC
  Nucleic Acids Res 2017, 45(18), 10492-503
  
• The E3 ubiquitin ligase APC/C(C)(dh1) degrades MCPH1 after MCPH1-βTrCP2-Cdc25A-mediated mitotic entry to ensure neurogenesis.
  Liu X, Zong W, Li T, Wang Y, Xu X, Zhou** ZW, Wang** ZQ
  EMBO J 2017, 36(24), 3666-81 ** co-corresponding authors
  
• Assessment of HDACi-Induced Cytotoxicity.
  Marx-Blümel L, Marx C, Kühne M, Sonnemann J
  Methods Mol Biol 2017, 1510, 23-45
  
• Telomerase abrogates aneuploidy-induced telomere replication stress, senescence and cell depletion.
  Meena JK, Cerutti A, Beichler C, Morita Y, Bruhn C, Kumar M, Kraus JM, Speicher MR, Wang ZQ, Kestler HA, Fagagna Fdd, Günes C, Rudolph KL
  EMBO J 2017, 36(19), 2922-4 Erratum for EMBO J 2015 volume 34 page 1371
  
• The Wilms tumor protein Wt1 contributes to female fertility by regulating oviductal proteostasis.
  Nathan A, Reinhardt P, Kruspe D, Jörß T, Groth M, Nolte H, Habenicht A, Herrmann J, Holschbach V, Toth B, Krüger M, Wang ZQ, Platzer M, Englert C
  Hum Mol Genet 2017, 26(9), 1694-705
  
• Central immune tolerance depends on crosstalk between the classical and alternative NF-κB pathways in medullary thymic epithelial cells.
  Riemann M, Andreas N, Fedoseeva M, Meier E, Weih D, Freytag H, Schmidt-Ullrich R, Klein U, Wang ZQ, Weih F
  J Autoimmun 2017, 81, 56-67
  
• The protein-tyrosine phosphatase DEP-1 promotes migration and phagocytic activity of microglial cells in part through negative regulation of fyn tyrosine kinase.
  Schneble N, Müller J, Kliche S, Bauer R, Wetzker R, Böhmer FD, Wang ZQ, Müller JP
  Glia 2017, 65(2), 416-28
  
• PARPing for Balance in the Homeostasis of Poly(ADP-ribosyl)ation.
  Schuhwerk H, Atteya R, Siniuk K, Wang ZQ
  Semin Cell Dev Biol 2017, 63, 81-91