2024

• Determinants of p53 DNA binding, gene regulation, and cell fate decisions.
  Fischer** * M, Sammons** * MA
  Cell Death Differ 2024, 31(7), 836-43 * equal contribution, ** co-corresponding authors
  
• Systematic computational hunting for small RNAs derived from ncRNAs during dengue virus infection in endothelial HMEC-1 cells.
  Gutierrez-Diaz A, Hoffmann S, Gallego-Gómez JC, Bermudez-Santana CI
  Front Bioinform 2024, 4, 1293412
  
• Bashing irreproducibility with shournal.
  Kirchner T, Riege K, Hoffmann S
  Sci Rep 2024, 14(1), 4872
  
• Pipeline Olympics: continuable benchmarking of computational workflows for DNA methylation sequencing data against an experimental gold-standard
  Lin YY, Breuer K, Weichenhan D, Lafrenz P, Wilk A, Chepeleva M, Mücke O, Schönung M, Petermann F, Kensche P, Weiser L, Thommen F, Giacomelli G, Nordstroem K, Gonzales-Avalos E, Merkel A, Kretzmer H, Fischer J, Krämer S, Iskar M, Wolf S, Buchhalter I, Esteller M, Lawerenz C, Twardziok S, Zapatka M, Hovestadt V, Schlesner M, Schulz M, Hoffmann S, Gerhauser C, Walter J, Hartmann M, B.Lipka D, Assenov Y, Bock C, Plass C, Toth R, Lutsik P
  bioRxiv 2024, https://doi.org/10.1101/2024.09.
  
• Nonlinear DNA methylation trajectories in aging male mice.
  Olecka* M, van Bömmel* A, Best L, Haase M, Foerste S, Riege K, Dost T, Flor S, Witte OW, Franzenburg S, Groth M, von Eyss B, Kaleta C, Frahm C, Hoffmann S
  Nat Commun 2024, 15(1), 3074 * equal contribution
  
• The Greenland shark (Somniosus microcephalus) genome provides insights into extreme longevity
  Sahm A, Cherkasov* A, Liu* H, Voronov D, Siniuk K, Schwarz R, Ohlenschlaeger O, Foerste S, Bens M, Groth M, Goerlich I, Paturej S, Klages S, Braendl B, Olsen J, Bushnell P, Bech Poulsen A, Ferrando S, Garibaldi F, Lorenzo Drago D, Terzibasi Tozzini E, Mueller FJ, Fischer M, Kretzmer H, Domenici** P, Fleng Steffensen** J, Cellerino** A, Hoffmann** S
  bioRxiv 2024, 10.1101/2024.09.09.611499 * equal contribution, ** co-corresponding authors
  
• Hydra has mammal-like mutation rates facilitating fast adaptation despite its nonaging phenotype.
  Sahm A, Riege K, Groth M, Bens M, Kraus J, Fischer M, Kestler H, Englert C, Schaible R, Platzer M, Hoffmann S
  Genome Res 2024, 34(12), 2217-28
  
• Circadian clock disruption engages the DREAM complex in suppressing cellular health
  Santos Valentim I, Javier Romero-Expósito F, Schwab K, Bayar M, Riege K, Fischer M, Olmedo M, Hoffmann S, A.Ermolaeva M
  bioRxiv 2024, https://doi.org/10.1101/2024.06.
  
• p53 target ANKRA2 cooperates with RFX7 to regulate tumor suppressor genes.
  Schwab K, Riege K, Coronel L, Stanko C, Förste S, Hoffmann** S, Fischer** M
  Cell Death Discov 2024, 10(1), 376 ** co-corresponding authors
  
• Npbwr1 signaling mediates fast antidepressant action.
  Stein G, Aly JS, Lange L, Manzolillo A, Riege K, Brancato A, Hübner CA, Turecki G, Hoffmann S, Engmann O
  Mol Psychiatry 2024 (epub ahead of print)