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  • p53 target ANKRA2 cooperates with RFX7 to regulate tumor suppressor genes.
    Schwab K, Riege K, Coronel L, Stanko C, Förste S, Hoffmann** S, Fischer** M
    Cell Death Discov 2024, 10(1), 376 ** co-corresponding authors
  • Mis-spliced transcripts generate de novo proteins in TDP-43-related ALS/FTD.
    Seddighi S, Qi YA, Brown AL, Wilkins OG, Bereda C, Belair C, Zhang YJ, Prudencio M, Keuss MJ, Khandeshi A, Pickles S, Kargbo-Hill SE, Hawrot J, Ramos DM, Yuan H, Roberts J, Sacramento EK, Shah SI, Nalls MA, Colón-Mercado JM, Reyes JF, Ryan VH, Nelson MP, Cook CN, Li Z, Screven L, Kwan JY, Mehta PR, Zanovello M, Hallegger M, Shantaraman A, Ping L, Koike Y, Oskarsson B, Staff NP, Duong DM, Ahmed A, Secrier M, Ule J, Jacobson S, Reich DS, Rohrer JD, Malaspina A, Dickson DW, Glass JD, Ori A, Seyfried NT, Maragkakis M, Petrucelli L, Fratta P, Ward ME
    Sci Transl Med 2024, 16(734), eadg7162
  • Reducing the metabolic burden of rRNA synthesis promotes healthy longevity in Caenorhabditis elegans.
    Sharifi* S, Chaudhari* P, Martirosyan A, Eberhardt AO, Witt F, Gollowitzer A, Lange L, Woitzat Y, Okoli EM, Li H, Rahnis N, Kirkpatrick J, Werz O, Ori A, Koeberle A, Bierhoff** H, Ermolaeva** M
    Nat Commun 2024, 15(1), 1702 * equal contribution, ** co-corresponding authors
  • Fe-S cluster biosynthesis in chromatin protects genome stability and promotes DNA replication
    Shi R
    Dissertation 2024, Jena, Germany
  • Tau mediates the reshaping of the transcriptional landscape toward intermediate Alzheimer's disease stages.
    Siano G, Varisco M, Terrigno M, Wang C, Scarlatti A, Iannone V, Groth M, Galas MC, Hoozemans JJM, Cellerino A, Cattaneo A, Di Primio C
    Front Cell Dev Biol 2024, 12, 1459573
  • Endothelial LATS2 is a suppressor of bone marrow fibrosis
    Sivaraj KK, Majev PG, Dharmalingam B, Schröder S, Banjanin B, Stehling M, Zeuschner D, Nordheim A, Schneider RK, Adams RH
    Nat Cardiovasc Res 2024, 3(8), 951-69
  • Sodium chloride in the tumor microenvironment enhances T cell metabolic fitness and cytotoxicity.
    Soll D, Chu CF, Sun S, Lutz V, Arunkumar M, Gachechiladze M, Schäuble S, Alissa-Alkhalaf M, Nguyen T, Khalil MA, Garcia-Ribelles I, Mueller M, Buder K, Michalke B, Panagiotou G, Ziegler-Martin K, Benz P, Schatzlmaier P, Hiller K, Stockinger H, Luu M, Schober K, Moosmann C, Schamel WW, Huber M, Zielinski CE
    Nat Immunol 2024, 25(10), 1830-44
  • Pyjacker identifies enhancer hijacking events in acute myeloid leukemia including MNX1 activation via deletion 7q
    Sollier E, Riedel A, H.Toprak U, A.Wierzbinska J, Weichenhan D, Philipp Schmid J, Hakobyan M, Touzart A, Jahn E, Vick B, Brown-Burke F, Kelly K, Kelekci S, Pejkovska A, Goyal A, Bähr M, Breuer K, May Chen MJ, Llamazares-Prada M, Hartmann M, Schönung M, Correia N, Trumpp A, Abdullah Y, Klingmüller U, S.Mughal S, Brors B, Westermann F, Schlesner M, Vosberg S, Herold T, A.Greif P, Pfeifer D, Lübbert M, Fischer T, H.Heidel F, Gebhard C, Walter W, Haferlach T, Eisfeld AK, Mrózek K, Nicolet D, Bullinger L, Smeenk L, Erpelinck C, Mulet-Lazaro R, Delwel R, Ernst A, Scherer M, Lutsik P, Jeremias I, Döhner K, Döhner H, B.Lipka D, Plass C
    bioRxiv 2024, https://doi.org/10.1101/2024.09.
  • The cytoskeletal protein Leiomodin 1 controls Sirtuin 1 localization during myogenic differentiation
    Späth E
    Dissertation 2024, Jena, Germany
  • Leiomodin 1 promotes myogenic differentiation by modulating Sirtuin 1
    Späth* E, C.Schüler* S, Heinze I, Dau T, Minetti A, Hofmann M, von Maltzahn** J, Ori** A
    bioRxiv 2024, https://doi.org/10.1101/2024.03. * equal contribution, ** co-corresponding authors