Welcome to the FLI

The Leibniz Institute on Aging – Fritz Lipmann Institute (FLI) is the first national research institute in Germany focusing on biomedical research on human aging, a multifactorial process controlled by environmental and genetic factors.


This website will provide you with an insight into our institute, the research we do and the faces behind FLI's science activities. We wish you an exciting and entertaining voyage of discovery into the world of aging research at FLI.



Since 2004, our mission has been to delineate basic molecular mechanisms that underlie the aging process in humans and its consequences for the development of aging-related cell and tissue dysfunction and diseases. Research at the FLI will provide a knowledge basis for the development of therapies aiming to facilitate healthy aging by prolonging organismal functions and disease prevention in the elderly.

In order to better correspond to this research focus, the institute was re-named from Leibniz Institute for Age Research into Leibniz Institute on Aging in 2015.

high impact publications

  • Aging-Induced Stem Cell Mutations as Drivers for Disease and Cancer.
    Adams* PD, Jasper* H, Rudolph* KL
    Cell Stem Cell 2015, 16(6), 601-12 * co-corresponding author
  • Stem Cells and Aging: What’s Next?
    Artandi SE, Blau HM, de Haan G, Geiger H, Goodell MA, Jones L, Levine RL, Munoz-Canoves P, Rodewald HR, Wagers A, Wang ZQ, Yamashita Y
    Cell Stem Cell 2015, 16, 578-81
  • From the bush to the bench: the annual Nothobranchius fishes as a new model system in biology.
    Cellerino A, Valenzano DR, Reichard M
    Biol Rev Camb Philos Soc 2015 (epub ahead of print)
  • Wip1 deficiency impairs haematopoietic stem cell function via p53 and mTORC1 pathways.
    Chen Z, Yi W, Morita Y, Wang H, Cong Y, Liu JP, Xiao Z, Rudolph KL, Cheng T, Ju Z
    Nat Commun 2015, 6, 6808
  • Interaction of the amyloid precursor protein-like protein 1 (APLP1) E2 domain with heparan sulfate involves two distinct binding modes.
    Dahms SO, Mayer MC, Roeser D, Multhaup G, Than ME
    Acta Crystallogr D Biol Crystallogr 2015, 71(Pt 3), 494-504
  • Towards an understanding of kidney diseases associated with WT1 mutations.
    Dong L, Pietsch S, Englert C
    Kidney Int 2015 (epub ahead of print)

FLI News

As of October 1st, 2015, the FLI presents itself with a new corporate design.

From September 22nd to 26th, the FLI participated in the Science Festival „Highlights der Physik”, which took place at Eichplatz, Jena. The FLI was...

The FLI participated in a soccer tournament to integrate refugees.