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Welcome to the Leibniz Institute on Aging (FLI)

The Leibniz Institute on Aging – Fritz Lipmann Institute (FLI) is the first national research institute in Germany focusing on biomedical research on human aging, a multifactorial process controlled by environmental and genetic factors.

This website will provide you with an insight into our institute, the research we do and the faces behind FLI's science activities. We wish you an exciting and entertaining voyage of discovery into the world of aging research at FLI.



Since 2004, our mission has been to delineate basic molecular mechanisms that underlie the aging process in humans and its consequences for the development of aging-related cell and tissue dysfunction and diseases. Research at the FLI will provide a knowledge basis for the development of therapies aiming to facilitate healthy aging by prolonging organismal functions and disease prevention in the elderly.

In order to better correspond to this research focus, the institute was re-named from Leibniz Institute for Age Research into Leibniz Institute on Aging in 2015.

recent high impact publications

  • Methylation-assisted bisulfite sequencing to simultaneously map 5fC and 5caC on a genome-wide scale for DNA demethylation analysis.
    Neri F, Incarnato D, Krepelova A, Parlato C, Oliviero S
    Nat Protoc 2016, 11(7), 1191-205 published during change of institution
  • NEMO Prevents RIP Kinase 1-Mediated Epithelial Cell Death and Chronic Intestinal Inflammation by NF-κB-Dependent and -Independent Functions.
    Vlantis K, Wullaert A, Polykratis A, Kondylis V, Dannappel M, Schwarzer R, Welz P, Corona T, Walczak H, Weih F, Klein U, Kelliher M, Pasparakis M
    Immunity 2016, 44(3), 553-67
  • p21 shapes cancer evolution.
    Romanov VS, Rudolph KL
    Nat Cell Biol 2016, 18(7), 722-4
  • DNA damage tolerance pathway involving DNA polymerase ι and the tumor suppressor p53 regulates DNA replication fork progression.
    Hampp S, Kiessling T, Buechle K, Mansilla SF, Thomale J, Rall M, Ahn J, Pospiech H, Gottifredi V, Wiesmüller L
    Proc Natl Acad Sci U S A 2016 (epub ahead of print)
  • Outgroups and Positive Selection: The Nothobranchius furzeri Case.
    Sahm A, Platzer M, Cellerino A
    Trends Genet 2016 (epub ahead of print)
  • Nothobranchius furzeri: A Model for Aging Research and More.
    Platzer M, Englert C
    Trends Genet 2016 (epub ahead of print)

Recent FLI Press Releases

Why do cells and tissues age and what are the genetic and molecular causes for aging? These are the central research questions that Italian junior...

Sechs internationale Forschertalente erhalten je bis zu 1,65 Millionen Euro Preisgeld und bauen damit in Halle/Saale, Heidelberg, Jena, Mainz und...

Die Else-Kröner-Fresenius-Stiftung fördert Forschungskarrieren junger Fachärzte am Uniklinikum Jena.

The population of Japan is ageing – just like that of Germany. Japanese scientists estimate that by 2030, 25.6 % of the country’s population will be...

Researchers from the Friedrich Schiller University Jena and Kiel University have compiled all metabolic pathways of the model organism Caenorhabditis...