CF Technology Transfer Unit (SPARK@FLI)
Translating discoveries from bench to bedside is a challenging process and allows us do advance scientific discoveries and ensures that government-funded research translates into improved health for our society. The SPARK training program helps to understand clinical needs, develops a target product profile and strengthens project management abilities. These essential tools not only increase the likelihood of success, but also help decrease both the cost and time required to accomplish this goal (“de-risking”).
The Transfer Unit supports research labs to develop small molecules or biologicals or treatments of unmet clinical needs, respectively, with the aim to advance projects for any indication with high potential impact. To achieve this goal we utilize a variety of molecular and cell based techniques as well as different animal models.
The facility offers advisory, financial and personnel support, including:
- Funds to asses and to de-risk your project
- Funds to actually run a project
- Implementation and execution of assays, e.g. toxicity assay, dose-response assay
- Advice from SPARK advisory board, consisting of experts with translational experience
- Mentored project management support
- Help to establish defensible Intellectual Property
- Training on what translation is all about
- Education on drug and diagnostic development
- Introduction to of the SPARK international network
We are currently using and offering support for the following assays and techniques:
- Cell culture (primary and tumor cell lines, mouse and human)
- Toxicity tests
- Viability tests
- Protein purification - see also Core Service Protein Production
- Western Blot analysis, RNA purification
- qPCR analysis
- siRNA & shRNA - see also Core Facility Functional Genomics
- virus production
The first call for projects has been placed, please contact S. Schaetzlein for further information (Submission deadline was February 15th 2016).
Project presentation date: TBA
Topics covered during our educational seminars will include (TBA):
- Intellectual property rights (overview on TT workshops (pdf))
- Material and Transfer agreements (MTA)
- Assay development
- Medicinal chemistry
- Target Product Profile (TPP)
- Drug Discovery and Development
- Funding opportunities
- High Throughput Screening (HTS)
A free sample of the published book, “SPARK: A Practical Guide to Drug Development in Academia”, by Daria Mochly-Rosen and Kevin Grimes will be given to our SPARKees.
Download (pdf) "SPARK Info Packet"
Please inquire – guest contract may be necessary.
|Sonja Schätzlein||+49 3641 firstname.lastname@example.org||Core Facility Manager|
|Frederike Kramer||+49 3641 email@example.com||Scientist|
|Sylke Pfeifer||+49 3641 firstname.lastname@example.org||Technical Assistant|
|Beate Szafranski||+49 3641 email@example.com||Technical Assistant|
|Christoph Kaether||+49 3641 firstname.lastname@example.org||Scientific Supervisor|