CF Life Science Computing
The CF Life Science Computing provides support to FLI scientists when the analysis of experimental data requires complex algorithms, advanced statistics or high performance computational power for processing. Often, this is the case for large scale omics data generated by work of other Core Facilities (CF Next Generation Sequencing, CF Proteomics, or CF Functional Genomics).
Towards computational resources, the facility maintains a Unix-based infrastructure and several software services for institute-wide use. Moreover, the facility offers custom bioinformatics and statistical analysis of research data as a service. In addition, research data management, not only of omics data, is supported by the operation of relevant software and databases as well as training and consultation on all related topics.
Computational Systems:
- Operate network of Unix clients, servers and storage units; support computational users
- Maintain community software, e.g. SGE, RStudio, GitLab
- Web hosting of scientific resources, e.g. Jena3D Viewer, Nothobranchius Genome Browser
Scientific Software Services:
- Operate central documentation software, e.g. Electronic Laboratory Notebook (ELN), long-term Data Archive (fliDA), animal databases
- Consultation for needs in scientific software, including custom developments
Bioinformatics & Statistics:
- Bioinformatics analyses on client's experimental data, in particular:
Differential expression analysis of omics experiments
Chromatin state experiments, e.g. ChIP-seq, ATAC-seq, CUT&Tag
Gene set / pathway enrichment analysis and effect modeling
Further directions upon requests
- Consultation and training on bioinformatics and biostatistics
Research Data Management (RDM):
- Optimize interoperation of electronic documentation systems (ELN, fliDA, databases) and coordination with experimental workflows
- Collect wishes and concerns regarding technical implementations of GSP / RDM tools, help with implementation and application
