Prof. Dr. Dr. Steve Hoffmann
Group Leader
One of our primary interests is to contribute to a better understanding of the epigenetic control of transcription. To do this, we are developing methods for the analysis of big and multidimensional biological data sets.
The Computational Biology Group is a young research team. One of our primary interests is to contribute to a better understanding of the epigenetic control of transcription. To do this, we are developing methods for the analysis of big and multidimensional biological data sets.
Our work is highly collaborative and we are and have been a member of several high-profile national and international consortia such as the International Cancer Genome Consortium (ICGC) or the BLUEPRINT Consortium.
The Greenland Shark (Somniosus microcephalus), an elusive dweller of the depths of the northern Atlantic and the Arctic Ocean, is the world’s longest-living vertebrate, with an estimated lifespan of about 400 years. An international team of scientists, including scientists from the Leibniz Institute on Aging – Fritz Lipmann Institute (FLI) I Jena, has mapped the Greenland Shark’s genome for the first time, and the data suggest that this animal’s toolbox for repairing its own DNA may explain its extreme longevity - and that of other animals.
Research teams from Leibniz Institute on Aging – Fritz Lipmann Institute Jena (FLI), University Hospital Jena and Christian-Albrechts-University Kiel identify sudden molecular changes during aging.
