Publications Project Biochemistry

2014

• Kinesin-dependent motility generation as target mechanism of cadmium intoxication.
  Böhm KJ
  Toxicol Lett 2014, 224(3), 356-61
  
• The intrinsically disordered amino-terminal region of human RecQL4: multiple DNA-binding domains confer annealing, strand exchange and G4 DNA binding.
  Keller H, Kiosze K, Sachsenweger J, Haumann S, Ohlenschläger O, Nuutinen T, Syväoja J, Görlach M, Grosse F, Pospiech H
  Nucleic Acids Res 2014, 42(20), 12614-27
  
• Using cells as biochemical test tubes: Comment on "Biomolecular dynamics and binding studies in the living cell" by Stephan Diekmann and Christian Hoischen.
  Koalick D, Grosse F
  Phys Life Rev 2014, 11(1), 33-5
  
• Suppression of the DHX9 helicase induces premature senescence in human diploid fibroblasts in a p53-dependent manner.
  Lee T, Di Paola D, Malina A, Mills JR, Kreps A, Grosse F, Tang H, Zannis-Hadjopoulos M, Larsson O, Pelletier J
  J Biol Chem 2014, 289(33), 22798-814
  
• Caspase-3 and Caspase-6 cleave STAT1 in leukemic cells.
  Licht* V, Noack* K, Schlott B, Förster M, Schlenker Y, Licht A, Krämer OH, Heinzel T
  Oncotarget 2014, 5(8), 2305-17 * equal contribution
  
• The Ca2+ sensor protein swiprosin-1/EFhd2 is present in neurites and involved in kinesin-mediated transport in neurons.
  Purohit P, Perez-Branguli F, Prots I, Borger E, Gunn-Moore F, Welzel O, Loy K, Wenzel EM, Grömer TW, Brachs S, Holzer M, Buslei R, Fritsch K, Regensburger M, Böhm KJ, Winner B, Mielenz D
  PLoS One 2014, 9(8), e103976
  
• DNA binding properties of human Cdc45 suggest a function as molecular wedge for DNA unwinding.
  Szambowska A, Tessmer I, Kursula P, Usskilat C, Prus P, Pospiech H, Grosse F
  Nucleic Acids Res 2014, 42(4), 2308-19
  
• Gap-directed translesion DNA synthesis of an abasic site on circular DNA templates by a human replication complex.
  Villani G, Shevelev I, Orlando E, Pospiech H, Syvaoja JE, Markkanen E, Hubscher U, Le Gac NT
  PLoS One 2014, 9(4), e93908
  

2013

• Characterization of a new class of androgen receptor antagonists with potential therapeutic application in advanced prostate cancer.
  Li H, Hassona MD, Lack NA, Axerio-Cilies P, Leblanc E, Kanaan N, Frewin K, Singh K, Adomat H, Böhm KJ, Prinz H, Guns ET, Rennie PS, Cherkasov A
  Mol Cancer Ther 2013, 12(11), 2425-35
  
• RNAi screening uncovers Dhx9 as a modifier of ABT-737 resistance in an Eμ-myc/Bcl-2 mouse model.
  Mills JR, Malina A, Lee T, Di Paola D, Larsson O, Miething C, Grosse F, Tang H, Zannis-Hadjopoulos M, Lowe SW, Pelletier J
  Blood 2013, 121(17), 3402-12