Former Jasper Cooperation Group (until 2018)



  • Cohesin controls intestinal stem cell identity by maintaining association of Escargot with target promoters.
    Khaminets A, Ronnen-Oron T, Baldauf M, Meier E, Jasper H
    Elife 2020, 9, e48160


  • The WT1-like transcription factor Klumpfuss maintains lineage commitment of enterocyte progenitors in the Drosophila intestine.
    Korzelius** J, Azami S, Ronnen-Oron T, Koch P, Baldauf M, Meier E, Rodriguez-Fernandez IA, Groth M, Sousa-Victor P, Jasper** H
    Nat Commun 2019, 10(1), 4123 ** co-corresponding authors
  • Loss of a proteostatic checkpoint in intestinal stem cells contributes to age-related epithelial dysfunction.
    Rodriguez-Fernandez IA, Qi Y, Jasper H
    Nat Commun 2019, 10(1), 1050
  • AWD regulates timed activation of BMP signaling in intestinal stem cells to maintain tissue homeostasis.
    Tracy Cai X, Li H, Safyan A, Gawlik J, Pyrowolakis G, Jasper H
    Nat Commun 2019, 10(1), 2988


  • Mutational impact of culturing human pluripotent and adult stem cells.
    Kuijk E, Jager M, van der Roest B, Locati M, Van Hoeck A, Korzelius J, Janssen R, Besselink N, Boymans S, van Boxtel R, Cuppen E
    bioRxiv 2018,


  • mTORC1 Activation during Repeated Regeneration Impairs Somatic Stem Cell Maintenance.
    Haller S, Kapuria S, Riley RR, O'Leary MN, Schreiber KH, Andersen JK, Melov S, Que J, Rando TA, Rock J, Kennedy BK, Rodgers JT, Jasper H
    Cell Stem Cell 2017, 21(6), 806-818.e5
  • Rejuvenating Strategies for Stem Cell-Based Therapies in Aging.
    Neves J, Sousa-Victor P, Jasper H
    Cell Stem Cell 2017, 20(2), 161-75


  • Metabolic regulation of stem cell function in tissue homeostasis and organismal ageing.
    Chandel NS, Jasper H, Ho TT, Passegué E
    Nat Cell Biol 2016, 18(8), 823-32
  • You Are What You Eat: Linking High-Fat Diet to Stem Cell Dysfunction and Tumorigenesis.
    Haller S, Jasper H
    Cell Stem Cell 2016, 18(5), 564-6
  • Intestinal IRE1 Is Required for Increased Triglyceride Metabolism and Longer Lifespan under Dietary Restriction.
    Luis NM, Wang L, Ortega M, Deng H, Katewa SD, Li PWL, Karpac J, Jasper** H, Kapahi** P
    Cell Rep 2016, 17(5), 1207-16 ** co-corresponding authors