Platzer Research Group (until 2018)

Publications

2019

  • C/EBPβ-LIP induces cancer-type metabolic reprogramming by regulating the let-7 /LIN28B circuit in mice.
    Ackermann T, Hartleben* G, Müller* C, Mastrobuoni G, Groth M, Sterken BA, Zaini MA, Youssef SA, Zuidhof HR, Krauss SR, Kortman G, de Haan G, de Bruin A, Wang ZQ, Platzer M, Kempa S, Calkhoven CF
    Commun Biol 2019, 2, 208 * equal contribution
  • Mitohormetic effects of rotenone drastically depend on age.
    Baumgart* M, Ugolini* M, Groth M, Platzer M, Cellerino A
    bioRxiv 2019, https://doi.org/10.1101/528547 * equal contribution
  • Comment on 'Naked mole-rat mortality rates defy Gompertzian laws by not increasing with age'.
    Dammann* P, Scherag* A, Zak N, Szafranski K, Holtze S, Begall S, Burda H, Kestler HA, Hildebrandt T, Platzer M
    Elife 2019, 8 * corresponding author
  • Publisher Correction: Transcriptomic alterations during ageing reflect the shift from cancer to degenerative diseases in the elderly.
    Irizar PA, Schäuble S, Esser D, Groth M, Frahm C, Priebe S, Baumgart M, Hartmann N, Marthandan S, Menzel U, Müller J, Schmidt S, Ast V, Caliebe A, König R, Krawczak M, Ristow M, Schuster S, Cellerino A, Diekmann S, Englert C, Hemmerich P, Sühnel J, Guthke R, Witte OW, Platzer M, Ruppin E, Kaleta C
    Nat Commun 2019, 10(1), 2459
  • Analysis of the coding sequences of clownfish reveals molecular convergence in the evolution of lifespan.
    Sahm A, Almaida-Pagán P, Bens M, Mutalipassi M, Lucas-Sánchez A, de Costa Ruiz J, Görlach M, Cellerino A
    BMC Evol Biol 2019, 19(1), 89

2018

  • Transcriptomic alterations during ageing reflect the shift from cancer to degenerative diseases in the elderly.
    Aramillo Irizar P, Schäuble S, Esser D, Groth M, Frahm C, Priebe S, Baumgart M, Hartmann N, Marthandan S, Menzel U, Müller J, Schmidt S, Ast V, Caliebe A, König R, Krawczak M, Ristow M, Schuster S, Cellerino A, Diekmann S, Englert C, Hemmerich P, Sühnel J, Guthke R, Witte OW, Platzer M, Ruppin E, Kaleta C
    Nat Commun 2018, 9(1), 327
  • DNA methylation of the rat Nr3c1 promoter and Igf2/H19 imprinting control regions and alterations after prenatal dexamethason treatment.
    Awazie OB
    Dissertation 2018, Jena, Germany
  • Naked mole-rat transcriptome signatures of socially suppressed sexual maturation and links of reproduction to aging.
    Bens* M, Szafranski* K, Holtze S, Sahm A, Groth M, Kestler HA, Hildebrandt** TB, Platzer** M
    BMC Biol 2018, 16(1), 77 * equal contribution, ** co-senior authors
  • Googles DeepVariant: eine Methode für die Medizin- und Bioinformatik?
    Fürstberger** A, Platzer** M, Kestler** HA
    BIOspektrum 2018, 24(3), 235–235 ** co-corresponding authors
  • Species comparison of liver proteomes reveals links to naked mole-rat longevity and human aging.
    Heinze* I, Bens* M, Calzia* E, Holtze S, Dakhovnik O, Sahm A, Kirkpatrick JM, Szafranski K, Romanov N, Sama SN, Holzer K, Singer S, Ermolaeva M, Platzer** M, Hildebrandt** T, Ori** A
    BMC Biol 2018, 16(1), 82 * equal contribution, ** co-senior authors
  • The microenvironment of naked mole-rat burrows in East Africa
    Holtze S, Braude S, Lemma A, Koch R, Morhart M, Szafranski K, Platzer M, Alemayehu F, Goeritz F, Hildebrandt TB
    Afr J Ecol 2018, 56(2), 279-89
  • 3D Network exploration and visualisation for lifespan data.
    Hühne* R, Kessler* V, Fürstberger* A, Kühlwein S, Platzer M, Sühnel J, Lausser L, Kestler HA
    BMC Bioinformatics 2018, 19(1), 390 * equal contribution
  • The high degree of cystathionine β-synthase (CBS) activation by S-adenosylmethionine (SAM) may explain naked mole-rat's distinct methionine metabolite profile compared to mouse.
    Olecka M, Huse K, Platzer M
    Geroscience 2018, 40(4), 359-60
  • Exploring the basis of naked mole-rat healthspan by characterization of its transsulfuration pathway and hydroxymethylome.
    Olecka MK
    Dissertation 2018, Jena, Germany
  • The Pseudogenes of Barley.
    Prade VM, Gundlach H, Twardziok S, Chapman B, Tan C, Langridge P, Schulman AH, Stein N, Waugh R, Zhang G, Platzer M, Li C, Spannagl M, Mayer KFX
    Plant J 2018, 93(3), 502-14
  • Impairing L-Threonine Catabolism Promotes Healthspan through Methylglyoxal-Mediated Proteohormesis.
    Ravichandran M, Priebe S, Grigolon G, Rozanov L, Groth M, Laube B, Guthke R, Platzer M, Zarse K, Ristow M
    Cell Metab 2018, 27(4), 914-25
  • Haplotypes composed of minor frequency single nucleotide polymorphism of tnf gene protect from progression into sepsis: A study using the new sepsis classification.
    Retsas T, Huse K, Lazaridis LD, Karampela N, Bauer M, Platzer M, Kolonia V, Papageorgiou E, Giamarellos-Bourboulis EJ, Dimopoulos G
    Int J Infect Dis 2018, 67, 102-6
  • Higher gene expression stability during aging in long-lived giant mole-rats than in short-lived rats.
    Sahm A, Bens M, Henning Y, Vole C, Groth M, Schwab M, Hoffmann S, Platzer* M, Szafranski* K, Dammann* P
    Aging (Albany NY) 2018, 10(12), 3938-56 * equal contribution
  • Long-lived rodents reveal signatures of positive selection in genes associated with lifespan.
    Sahm A, Bens M, Szafranski K, Holtze S, Groth M, Görlach M, Calkhoven C, Müller C, Schwab M, Kraus J, Kestler HA, Cellerino A, Burda H, Hildebrandt T, Dammann P, Platzer M
    PLoS Genet 2018, 14(3), e1007272
  • The Definition of Open Reading Frame Revisited.
    Sieber P, Platzer M, Schuster S
    Trends Genet 2018, 34(3), 167-70