Transcriptomic alterations during ageing reflect the shift from cancer to degenerative diseases in the elderly. Aramillo Irizar P, Schäuble S, Esser D, Groth M, Frahm C, Priebe S, Baumgart M, Hartmann N, Marthandan S, Menzel U, Müller J, Schmidt S, Ast V, Caliebe A, König R, Krawczak M, Ristow M, Schuster S, Cellerino A, Diekmann S, Englert C, Hemmerich P, Sühnel J, Guthke R, Witte OW, Platzer M, Ruppin E, Kaleta C Nat Commun 2018, 9(1), 327
DNA methylation of the rat Nr3c1 promoter and Igf2/H19 imprinting control regions and alterations after prenatal dexamethason treatment Awazie OB Dissertation 2018, Jena, Germany
Naked mole-rat transcriptome signatures of socially suppressed sexual maturation and links of reproduction to aging. Bens* M, Szafranski* K, Holtze S, Sahm A, Groth M, Kestler HA, Hildebrandt** TB, Platzer** M BMC Biol 2018, 16(1), 77 * equal contribution, ** co-senior authors
Species comparison of liver proteomes reveals links to naked mole-rat longevity and human aging. Heinze* I, Bens* M, Calzia* E, Holtze S, Dakhovnik O, Sahm A, Kirkpatrick JM, Szafranski K, Romanov N, Sama SN, Holzer K, Singer S, Ermolaeva M, Platzer** M, Hildebrandt** T, Ori** A BMC Biol 2018, 16(1), 82 * equal contribution, ** co-senior authors
The microenvironment of naked mole-rat burrows in East Africa Holtze S, Braude S, Lemma A, Koch R, Morhart M, Szafranski K, Platzer M, Alemayehu F, Goeritz F, Hildebrandt TB Afr J Ecol 2018, 56(2), 279-89
3D Network exploration and visualisation for lifespan data. Hühne* R, Kessler* V, Fürstberger* A, Kühlwein S, Platzer M, Sühnel J, Lausser L, Kestler HA BMC Bioinformatics 2018, 19(1), 390 * equal contribution
The high degree of cystathionine β-synthase (CBS) activation by S-adenosylmethionine (SAM) may explain naked mole-rat's distinct methionine metabolite profile compared to mouse. Olecka M, Huse K, Platzer M Geroscience 2018, 40(4), 359-60
Exploring the basis of naked mole-rat healthspan by characterization of its transsulfuration pathway and hydroxymethylome Olecka MK Dissertation 2018, Jena, Germany
The Pseudogenes of Barley. Prade VM, Gundlach H, Twardziok S, Chapman B, Tan C, Langridge P, Schulman AH, Stein N, Waugh R, Zhang G, Platzer M, Li C, Spannagl M, Mayer KFX Plant J 2018, 93(3), 502-14
Impairing L-Threonine Catabolism Promotes Healthspan through Methylglyoxal-Mediated Proteohormesis. Ravichandran M, Priebe S, Grigolon G, Rozanov L, Groth M, Laube B, Guthke R, Platzer M, Zarse K, Ristow M Cell Metab 2018, 27(4), 914-25
Haplotypes composed of minor frequency single nucleotide polymorphism of tnf gene protect from progression into sepsis: A study using the new sepsis classification. Retsas T, Huse K, Lazaridis LD, Karampela N, Bauer M, Platzer M, Kolonia V, Papageorgiou E, Giamarellos-Bourboulis EJ, Dimopoulos G Int J Infect Dis 2018, 67, 102-6
Clownfishes are a genetic model of exceptional longevity and reveal molecular convergence in the evolution of lifespan Sahm A, Almaida-Pagan P, Bens M, Mutalipassi M, Lucas-Sanchez A, de Costa Ruiz J, Goerlach M, Cellerino A bioRxiv 2018, https://doi.org/10.1101/380709
Higher gene expression stability during aging in long-lived giant mole-rats than in short-lived rats. Sahm A, Bens M, Henning Y, Vole C, Groth M, Schwab M, Hoffmann S, Platzer* M, Szafranski* K, Dammann* P Aging (Albany NY) 2018, 10(12), 3938-56 * equal contribution
Long-lived rodents reveal signatures of positive selection in genes associated with lifespan. Sahm A, Bens M, Szafranski K, Holtze S, Groth M, Görlach M, Calkhoven C, Müller C, Schwab M, Kraus J, Kestler HA, Cellerino A, Burda H, Hildebrandt T, Dammann P, Platzer M PLoS Genet 2018, 14(3), e1007272
The Definition of Open Reading Frame Revisited. Sieber P, Platzer M, Schuster S Trends Genet 2018, 34(3), 167-70
Rapidly evolving changes and gene loss associated with host switching in Corynebacterium pseudotuberculosis. Viana MVC, Sahm A, Góes Neto A, Figueiredo HCP, Wattam AR, Azevedo V PLoS One 2018, 13(11), e0207304
2017
Tissue-, sex- and age-specific DNA methylation of rat glucocorticoid receptor gene promoter and insulin like growth factor 2 imprinting control region. Agba OB, Lausser L, Huse K, Bergmeier C, Jahn N, Groth M, Bens M, Sahm A, Gall M, Witte OW, Kestler HA, Schwab M, Platzer M Physiol Genomics 2017, 49(11), 690-702 APSselect for distinction in scholarship in the Physiological Genomics
A miRNA catalogue and ncRNA annotation of the short-living fish Nothobranchius furzeri. Baumgart* M, Barth* E, Savino A, Groth M, Koch P, Petzold A, Arisi I, Platzer M, Marz* M, Cellerino* A BMC Genomics 2017, 18(1), 693 * equal contribution
Construction of a map-based reference genome sequence for barley, Hordeum vulgare L. Beier S, Himmelbach A, Colmsee C, Zhang XQ, Barrero RA, Zhang Q, Li L, Bayer M, Bolser D, Taudien S, Groth M, Felder M, Hastie A, Šimková H, Staňková H, Vrána J, Chan S, Muñoz-Amatriaín M, Ounit R, Wanamaker S, Schmutzer T, Aliyeva-Schnorr L, Grasso S, Tanskanen J, Sampath D, Heavens D, Cao S, Chapman B, Dai F, Han Y, Li H, Li X, Lin C, McCooke JK, Tan C, Wang S, Yin S, Zhou G, Poland JA, Bellgard MI, Houben A, Doležel J, Ayling S, Lonardi S, Langridge P, Muehlbauer GJ, Kersey P, Clark MD, Caccamo M, Schulman AH, Platzer M, Close TJ, Hansson M, Zhang G, Braumann I, Li C, Waugh R, Scholz U, Stein N, Mascher M Sci Data 2017, 4, 170044
Development and application of RNA-seq bioinformatic tools to explore non-model organisms in ageing research Bens M Dissertation 2017, Jena, Germany
