Success Stories
The following projects have been supported by the CF Technology Transfer Program SPARK-FLI and successfully acquired follow on third party, non-dilutive money:
The new research project “KreDiT RNA” investigates ribosomal RNA in cancer and aging processes (LINK)
YAP-Blocker: Neue Erkenntnisse bei Leberkrebs (Wilhelm Sander-Stiftung) (LINK)
Microbiome-based therapy for intestinal barrier protection (LINK)
FLI expands its capacities with the new "Experimental and Transgenesis Unit Fish" (LINK)
- GoBioInitial Sondierungsphase: Debdas Paul (2024)
- GoBioInitial Sondierungsphase: Kanstantsin Siniuk (2023)
- BMBF-Confirmatory Study: Helen Morrison (2020)
- BMBF-Target Validation: Björn von Eyss (2020)
Current projects
| Project | Field of invention | Medical area | Looking for |
|---|---|---|---|
| Peptide replacement therapy for treatment of Schwann cell-derived nerve sheath tumors | Pharma - Peptide | Oncology (Orphan Drug) | Industry Cooperation - Licensing |
| Novel target for tripple negative breast cancer therapy | Pharma - Small molecule | Oncology | Industry Cooperation - Licensing |
| The nucleolus: Biomarker and target for healthy aging | IVD | Aging | Industry Cooperation - Licensing |
| ProteasomeID for direct target validation of protein degraders | Platform - PROTAC | Oncology | Industry Cooperation - Licensing |
| Novel treatment for inherited mitochondrial deficiencies | Pharma - Small molecule | Mitochondrial diseases | Industry Cooperation - Licensing |
| Validation of the putative natural Wnt inhibitor for healthy aging and cancer treatment. | Pharma - Small molecule | Oncology | Industry Cooperation - Licensing |
| Pharmaceutical intervention against neurodegeneration in killifish | Platform | Neurodegeneration | Industry Cooperation - Licensing |
| Identification of RFX7-activating compounds | Pharma - Small molecule | Oncology | Industry Cooperation - Licensing |
| Modulation of the gut microbiota over small RNAs to improve stroke outcome | Pharma - RNA | Stroke | Industry Cooperation - Licensing |
| Counteracting health effects of sleep disruption by specific DREAM Inhibitors | Pharma - Small molecule | Sleep | Industry Cooperation - Licensing |
| Multi-tissue ageing clock for human | AI-Clock | Platfrom | Industry Cooperation - Licensing |
| Designing YAP/TAZ inhibitors | Pharma - Small molecule | Oncology | Industry Cooperation - Licensing |
| Novel measure of leaky gut through microbial profiling | IVD - Biomarker | IBD | Industry Cooperation - Licensing |
| Screening for biomarkers of neurofibromatosis and schwannomatosis | IVD - Biomarker | Oncology | Industry Cooperation - Licensing |
| Metabolites as targets or adjuvants of AD therapy | Pharma - Metabolite | AD | Industry Cooperation - Licensing |
| Preventing amyloid-beta precursor protein associated brain degeneration | Pharma - Small molecule | Neurodegeneration (AD) | Industry Cooperation - Licensing |
| ER morphology & lysosomal motility restoration platform | Pharma - Small molecule | Neurodengenration (orphon) | Industry Cooperation - Licensing |