The ATR-Activation Domain of TopBP1 Is Required for the Suppression of Origin Firing during the S Phase. Sokka* M, Koalick* D, Hemmerich P, Syväoja JE, Pospiech H Int J Mol Sci 2018, 19(8) * equal contribution
2017
Toxic effects of zinc ions on kinesin - Potential molecular cause of impaired intracellular transport. Böhm KJ Toxicol Lett 2017, 268, 58-62
N-Heterocyclic (4-Phenylpiperazin-1-yl)methanones Derived from Phenoxazine and Phenothiazine as Highly Potent Inhibitors of Tubulin Polymerization. Prinz H, Ridder AK, Vogel K, Böhm KJ, Ivanov I, Ghasemi J, Aghaee E, Müller K: J Med Chem 2017, 60(2), 749-66
Cdc45-induced loading of human RPA onto single-stranded DNA. Szambowska A, Tessmer I, Prus P, Schlott B, Pospiech H, Grosse F Nucleic Acids Res 2017, 45(6), 3217-30
2016
S100A11 plays a role in homologous recombination and genome maintenance by influencing the persistence of RAD51 in DNA repair foci. Foertsch F, Szambowska A, Weise A, Zielinski A, Schlott B, Kraft F, Mrasek K, Borgmann K, Pospiech** H, Grosse F, Melle** C Cell Cycle 2016, 15(20), 2766-79 ** co-corresponding authors
DNA damage tolerance pathway involving DNA polymerase ι and the tumor suppressor p53 regulates DNA replication fork progression. Hampp S, Kiessling T, Buechle K, Mansilla SF, Thomale J, Rall M, Ahn J, Pospiech H, Gottifredi V, Wiesmüller L Proc Natl Acad Sci U S A 2016, 113(30), E4311-9
Human DNA polymerase α interacts with mismatch repair proteins MSH2 and MSH6. Itkonen HM, Kantelinen J, Vaara M, Parkkinen S, Schlott B, Grosse F, Nyström M, Syväoja JE, Pospiech H FEBS Lett 2016, 590(23), 4233-41
Cdc45 is limiting for replication initiation in humans. Köhler C, Koalick D, Fabricius A, Parplys AC, Borgmann K, Pospiech H, Grosse F Cell Cycle 2016, 15(7), 974-85 ** co-senior authors
High-Content Microscopy Analysis of Subcellular Structures: Assay Development and Application to Focal Adhesion Quantification. Kroll* T, Schmidt* D, Schwanitz G, Ahmad M, Hamann J, Schlosser C, Lin YC, Böhm KJ, Tuckermann J, Ploubidou A Curr Protoc Cytom 2016, 77, 12.43.1-12.43.44 * equal contribution
Heterozygous PALB2 c.1592delT mutation channels DNA double-strand break repair into error-prone pathways in breast cancer patients. Obermeier K, Sachsenweger J, Friedl TWP, Pospiech H, Winqvist R, Wiesmüller L Oncogene 2016, 35(29), 3796-806
